Neurology and Neurosurgery

Below are current clinical trials.

129 studies in Neurology and Neurosurgery
(open studies only).

Filter this list of studies by location, status and more.

1. Cerebrovascular Diseases Prospective Registry

   Rochester, Minn.

   The purpose of this study is for genetic analysis of specimens removed during cerebrovascular neurosurgery to better understand pathophysiology of cerebrovascular pathology. 

    

    

2. A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases

   Rochester, Minn.

   The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve.

3. A Study of Factors That Predispose, Promote, and Perpetuate Post-Traumatic Dizziness

   Rochester, Minn.

   The purpose of this study is to investigate whether recent, groundbreaking discoveries about key pathophysiologic processes that drive chronic dizziness in patients without traumatic brain injury (TBI9,10) are applicable to patients with post-mTBI vestibular disability. We expect the results of this project to have practical clinical and research applications, providing novel data for two future steps:

4. A Long Term Study of Molecular and Structural Imaging in Atypical Alzheimer's Disease

   Rochester, Minn.

   The purpose of this study is to learn more about amyloid and tau burden in the brain of patients with Atypical Alzheimer's Disease and how that burden may change over a two-year period.

5. A Study of Molecular Anatomic Imaging Analysis of Tau, the Primary Pathological Protein in Progressive Supranuclear Palsy

   Rochester, Minn.

   The purpose of this study is to learn more about the distribution of the pathological protein tau in the living brains of patients with Progressive Supranuclear Palsy (PSP).

6. A Study to Evaluate Droperidol Use in the Emergency Department and the Effect on QTc

   Rochester, Minn.

   The purpose of this study is to study the length of the QTc interval in patients receiving the standard of care dose of intravenous droperidol for headache or migraine, nausea, pain, and indications other than agitation over 30 minutes.

7. A Study to Develop and Assess the Role of Artificial Intelligence in MR Fingerprinting of the Brain

   Rochester, Minn.

   The purpose of this study is to develop an artificial intelligence (AI) system than can process MR images acquired using conventional acquisition schemes (spin echo, gradient echo, etc) and contrasts (T1, T2, T2*, PD) to identify the MR fingerprint of the tissue under interrogation.

8. A Study to Collect Blood DNA Samples from Patients with Clinically Diagnosed Alzheimers Disease, Lewy Body Disease, and Frontotemporal Degeneration

   Rochester, Minn.

   The purpose of this study is to collect blood samples for DNA analysis from patients clinically diagnosed with Alzheimers disease, Lewy Body disease, and Frontotemporal degeneration.

9. Cognitive Advancement and Recovery in VNS-Rehabilitation (CARE)

   Rochester, Minn.

   The purpose of this study is to investigate whether VNS therapy leads to any changes in the cognitive functions of individuals who have survived a stroke.

10. Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases

    Jacksonville, Fla.

    The purpose of this study is to create a repository for cerebellar ataxia and nucleotide repeat diseases in order to fully investigate the genetic and phenotypic presentations of both.