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At Mayo Clinic, laser interstitial thermal therapy (LITT) is provided by a multidisciplinary team of specialists. Experts in brain surgery (neurosurgeons) work closely with experts in nonsurgical treatments (neurosurgeons and neuroradiologists) to evaluate each person and plan treatment using advanced imaging and minimally invasive techniques.

For epilepsy, Mayo Clinic most commonly uses LITT to treat temporal lobe epilepsy, especially when seizures begin in deep structures of the brain. Care teams carefully evaluate imaging, seizure patterns and overall health to determine whether LITT or another surgical approach is most appropriate.

In addition to epilepsy, Mayo Clinic uses LITT to treat:

  • Tumors that are resistant to radiation.
  • Tumors located in areas that are hard to reach with open surgery.
  • Radiation-induced changes in the brain.
  • Some palliative tumor situations where traditional surgery may not be ideal.

For brain tumors, LITT may be used when a tumor is deep in the brain, located near important functional areas or has returned after prior treatment. It also may be considered for certain cases of radiation-related brain changes.

Mayo Clinic's world-renowned neurosurgeons are highly trained and experienced in performing surgeries on many types of brain tumors. At Mayo Clinic, top-ranked doctors and specialists from the Brain Tumor Program work together with Mayo Clinic doctors and surgeons trained in conditions of the nervous system (neurologists and neurosurgeons).

Your team members may include:

  • Medical oncologists.
  • Neurologists.
  • Neuro-oncologists.
  • Neuropathologists.
  • Neuroradiologists.
  • Neurosurgeons.
  • Radiation oncologists.
  • Rehabilitation specialists.
  • Other specialists, as needed.

Although open surgery may offer a higher chance of seizure freedom in some cases, LITT remains an important option for carefully selected people. If LITT does not achieve the desired result, additional treatment options may still be available.

Mayo Clinic specialists continue to study and refine the use of LITT through research and clinical trials, with the goal of improving outcomes and expanding access to minimally invasive brain treatment.

Innovation

Mayo Clinic was an early adopter of LITT and has extensive experience using this approach for both epilepsy and certain brain tumors. The procedure is performed with real-time MRI guidance, allowing surgeons to precisely target deep areas of the brain through a small opening in the skull. This approach may reduce disruption to surrounding tissue and can shorten recovery time compared with traditional open surgery.

State-of-the-art technology

Mayo Clinic is a leader in neurosurgery. Doctors, surgeons and other healthcare professionals use state-of-the-art facilities that include an intraoperative MRI suite, comprehensive intraoperative neuromonitoring and image-guided surgery.

People who seek care at Mayo Clinic have access to the most advanced imaging and diagnostic tools available. There's a long history of Mayo Clinic scientists developing these and other cutting-edge technologies for patient care.

Mayo Clinic neuropathologists are skilled in analyzing brain tumor tissue in the lab to make an accurate diagnosis. They analyze many tissue samples every year and have access to the latest in lab technology. Neuropathologists at Mayo Clinic have experience in diagnosing all types of brain tumors, including very rare types. Getting an accurate diagnosis helps your healthcare team create the most effective treatment plan for you.

Experiencia y clasificación

Obtén más información sobre la experiencia y las clasificaciones de los departamentos de neurología y neurocirugía de Mayo Clinic.

El Centro Oncológico Integral de Mayo Clinic cumple con los estándares estrictos de un centro oncológico integral del Instituto Nacional del Cáncer de los EE. UU. Estos estándares reconocen la excelencia científica y un enfoque multidisciplinario centrado en la prevención, el diagnóstico y el tratamiento del cáncer.

Otra información sobre facturación y seguro:

Mayo Clinic en Arizona, Florida y Minnesota

Sistema de Salud de Mayo Clinic

May 13, 2026
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Laser interstitial thermal therapy (LITT)