Drug information provided by: Merative, Micromedex®
It is important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it. Blood, urine, and other laboratory tests may be needed to check for unwanted effects. If your condition does not improve, or if it becomes worse, discuss this with your doctor.
Do not use this medicine together rilpivirine (Edurant®) or products containing rilpivirine (eg, Complera®, Odefsey®), dihydroergotamine (Migranal®), ergotamine (Cafergot®), pimozide (Olap®), lomitapide (Juxtapid®), lovastatin (Mevacor®), lurasidone (Latuda®), or simvastatin (Zocor®). Do not use this medicine together with colchicine (Colcrys®) if you have kidney disease or liver disease. Using these medicines together may increase risk for more serious side effects.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment with this medicine. If you think you have become pregnant while using the medicine, tell your doctor right away.
Talk with your doctor before using this medicine if you plan to have children. Some men who use this medicine have become infertile (unable to have children).
This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have chest tightness, rash, itching, fast heartbeat, trouble breathing or swallowing, or large, hive-like swelling of the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs while you are using this medicine.
Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, or unusual tiredness or weakness. These may be symptoms of serious skin reactions, including Stevens-Johnson syndrome, acute generalized exanthematous pustulosis (AGEP), toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS).
This medicine may cause hypoglycemia (low blood sugar). This is more common when this medicine is taken together with insulin or oral diabetes medicines. Low blood sugar must be treated before it causes you to pass out (unconsciousness). People feel different symptoms of low blood sugar. It is important that you learn which symptoms you usually have so you can treat it quickly. Talk to your doctor about the best way to treat low blood sugar.
This medicine may cause drowsiness, trouble with thinking, or trouble with controlling body movements when used together with midazolam (Versed®), quetiapine (Seroquel®), or triazolam (Halcion®). Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
This medicine may increase the risk of bleeding when used together with a blood thinner (eg, warfarin). Check with your doctor right away if you have bleeding gums, coughing up blood, difficulty in breathing or swallowing, dizziness, headache, increased menstrual flow or vaginal bleeding, nosebleeds, paralysis, prolonged bleeding from cuts, red or dark brown urine, or red or black, tarry stools.
This medicine may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop taking this medicine. Do not take any medicine to treat diarrhea without first checking with your doctor. If you have any questions or if mild diarrhea continues or gets worse, check with your doctor.
Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
Check with your doctor right away if you have pain or tenderness in the fever with or without chills, upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Make sure your doctor knows if you had a heart rhythm problem, such as QT prolongation and torsade de pointes.
This medicine may cause myasthenia gravis (severe muscle weakness). Check with your doctor right away if you have difficulty in breathing, chewing, swallowing, or talking, double vision, drooping eyelids, muscle weakness, or severe tiredness.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St John's wort) or vitamin supplements.