Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding gums
  3. bloating or swelling of the face, arms, hands, lower legs, or feet
  4. blood in the urine or stools
  5. confusion
  6. cough
  7. crying
  8. delusions of persecution, mistrust, suspiciousness, or combativeness
  9. diarrhea
  10. difficult or labored breathing
  11. dysphoria
  12. false beliefs that cannot be changed by facts
  13. false or unusual sense of well-being
  14. feeling of unreality
  15. fever
  16. general feeling of discomfort or illness
  17. headache
  18. hoarseness
  19. joint pain
  20. loss of appetite
  21. lower back or side pain
  22. mental depression
  23. muscle aches and pains
  24. nausea
  25. nervousness
  26. painful or difficult urination
  27. pinpoint red spots on the skin
  28. poor insight and judgment
  29. problems with memory or speech
  30. quick to react or overreact emotionally
  31. rapid weight gain
  32. rapidly changing moods
  33. runny nose
  34. sense of detachment from self or body
  35. shakiness in the legs, arms, hands, or feet
  36. shivering
  37. sleepiness or unusual drowsiness
  38. sore throat
  39. sweating
  40. tightness in the chest
  41. tingling of the hands or feet
  42. trembling or shaking of the hands or feet
  43. trouble recognizing objects
  44. trouble sleeping
  45. trouble thinking and planning
  46. trouble walking
  47. unusual bleeding or bruising
  48. unusual tiredness or weakness
  49. unusual weight gain or loss
  50. vomiting

Less common

  1. Abnormal dreams
  2. absence of or decrease in body movement
  3. anxiety
  4. bloody nose
  5. bloody or cloudy urine
  6. blurred vision
  7. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  8. change in personality
  9. change in walking and balance
  10. changes in patterns and rhythms of speech
  11. chest pain
  12. clumsiness or unsteadiness
  13. cold sweats
  14. constipation
  15. dark urine
  16. deep or fast breathing with dizziness
  17. degenerative disease of the joint
  18. difficulty with moving
  19. discouragement
  20. dizziness
  21. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  22. dry mouth
  23. excessive muscle tone
  24. fast, irregular, pounding, or racing heartbeat or pulse
  25. fear
  26. feeling of warmth or heat
  27. feeling sad or empty
  28. flushing or redness of the skin, especially on the face and neck
  29. frequent urge to urinate
  30. heavy non-menstrual vaginal bleeding
  31. increased need to urinate
  32. indigestion
  33. irritability
  34. lack of appetite
  35. lack of coordination
  36. large, flat, blue or purplish patches in the skin
  37. leg cramps
  38. lip smacking or puckering
  39. loss of bladder control
  40. loss of interest or pleasure
  41. loss of strength or energy
  42. multiple swollen and inflamed skin lesions
  43. muscle pain or stiffness
  44. muscle tension or tightness
  45. normal menstrual bleeding occurring earlier, possibly lasting longer than expected
  46. numbness of the feet, hands and around mouth
  47. pains in the stomach, side, or abdomen, possibly radiating to the back
  48. passing urine more often
  49. pounding in the ears
  50. puffing of the cheeks
  51. rapid or worm-like movements of the tongue
  52. rapid weight gain
  53. restlessness
  54. seeing, hearing, or feeling things that are not there
  55. shakiness and unsteady walk
  56. slurred speech
  57. small red or purple spots on the skin
  58. sweating
  59. swollen joints
  60. tiredness
  61. trouble with concentrating
  62. trouble with speaking
  63. twitching
  64. uncontrolled chewing movements
  65. uncontrolled movements of the arms and legs
  66. unsteadiness, trembling, or other problems with muscle control or coordination
  67. vomiting of blood or material that looks like coffee grounds
  68. yellow eyes or skin

Incidence not known

  1. Aggression
  2. bladder pain
  3. blistering, peeling, loosening of the skin
  4. blisters on the skin
  5. bone pain, tenderness, or aching
  6. chest discomfort
  7. cloudy urine
  8. decrease in height
  9. decreased urine output
  10. difficulty swallowing
  11. feeling that others are watching you or controlling your behavior
  12. feeling that others can hear your thoughts
  13. feeling, seeing, or hearing things that are not there
  14. hives, itching, skin rash
  15. increased sensitivity of the skin to sunlight
  16. increased thirst
  17. irritability
  18. joint or muscle pain
  19. loss of balance control
  20. loss of consciousness
  21. mask-like face
  22. pain in the back, ribs, arms, or legs
  23. pain or swelling in the arms or legs without any injury
  24. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  25. red skin lesions, often with a purple center
  26. red, irritated eyes
  27. redness or other discoloration of the skin
  28. seizures
  29. severe mood or mental changes
  30. severe sunburn
  31. shuffling walk
  32. slow heartbeat
  33. slowed movements
  34. slurred speech
  35. sores, ulcers, or white spots in the mouth or on the lips
  36. stiffness of the arms and legs
  37. swelling of the face, ankles, or hands
  38. swollen or painful glands
  39. tic-like (jerky) movements of the head, face, mouth, and neck
  40. unusual behavior

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Change in consciousness
  2. fainting
  3. loss of consciousness
  4. slow or irregular heartbeat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Belching
  2. body aches or pain
  3. change in vision
  4. congestion
  5. continuing ringing or buzzing or other unexplained noise in the ears
  6. hair loss or thinning of the hair
  7. hearing loss
  8. heartburn
  9. impaired vision
  10. lack or loss of strength
  11. loss of memory
  12. problems with memory
  13. seeing double
  14. tender, swollen glands in the neck
  15. uncontrolled eye movements
  16. voice changes
  17. weight gain
  18. weight loss

Less common

  1. Absent, missed, or irregular menstrual periods
  2. burning, dry, or itching eyes
  3. change in taste or bad unusual or unpleasant (after) taste
  4. coin-shaped lesions on the skin
  5. cough producing mucus
  6. cramps
  7. dandruff
  8. discharge or excessive tearing
  9. dry skin
  10. earache
  11. excess air or gas in the stomach or bowels
  12. eye pain
  13. feeling of constant movement of self or surroundings
  14. full feeling
  15. heavy bleeding
  16. increased appetite
  17. itching of the vagina or genital area
  18. loss of bowel control
  19. neck pain
  20. oily skin
  21. pain
  22. pain during sexual intercourse
  23. pain or tenderness around the eyes and cheekbones
  24. passing gas
  25. rash with flat lesions or small raised lesions on the skin
  26. redness or swelling in the ear
  27. redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  28. redness, swelling, or soreness of the tongue
  29. sensation of spinning
  30. sneezing
  31. stiff neck
  32. stopping of menstrual bleeding
  33. thick, white vaginal discharge with no odor or with a mild odor

Incidence not known

  1. Breast enlargement
  2. changes in hair color or texture
  3. discoloration of the fingernails or toenails
  4. increased hair growth, especially on the face
  5. unexpected or excess milk flow from the breasts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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