Proper Use

Drug information provided by: Merative, Micromedex®

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot under the skin or into a muscle.

Urofollitropin is used with another hormone called human chorionic gonadotropin (hCG). At the proper time, your doctor or nurse will give you this medicine.

This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

You might be taught how to give your medicine at home. If you are using this medicine at home:

  • Wash your hands with soap and water and use a clean work area to prepare your injection.
  • Make sure you understand and carefully follow your doctor's instructions on how to give yourself an injection, including the proper use of a needle and syringe.
  • Check the solution in the vial. It should be clear and colorless. If it is cloudy, discolored, or contains large particles, do not use it.
  • Do not inject more or less of the medicine than your doctor ordered.
  • You will be shown the body areas (eg, stomach) where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will prevent skin problems.
  • Use a new needle and syringe each time you inject your medicine.
  • It is very important that you keep track of each dose you inject. Your doctor or nurse will help you with this.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For becoming pregnant while having a condition called polycystic ovary syndrome:
      • Adults—75 International Units (IU) injected under the skin or into a muscle once a day for 7 or more days. Your doctor will give you another medicine called chorionic gonadotropin (hCG) the day after the last dose. Your doctor will increase your dose to 150 IU per day for another 7 or more days, if needed.
      • Children—Use is not recommended.
    • For induction of ovulation in women:
      • Adults—At first, 150 International Units (IU) injected under the skin or into a muscle once a day for 5 days in the first cycle of treatment. Your doctor will adjust your dose after 5 days, if needed. However, the dose is usually not more than 450 IU per day. Do not use this medicine for more than 12 days.
      • Children—Use is not recommended.
    • For women with healthy ovaries undergoing assisted reproductive technology (ART):
      • Adults—At first, 225 International Units (IU) (150 IU of Bravelle® and 75 IU of Menopur® or 75 IU of Bravelle® and 150 IU of Menopur®) injected under the skin once a day. Your doctor will adjust your dose after 5 days, if needed. However, the dose is usually not more than 450 IU per day. Do not use this medicine for more than 12 days.
      • Children—Use is not recommended.

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the unused medicine in the refrigerator or at room temperature, protect from light. After mixing, use it immediately. Throw away any unused mixed medicine.

Throw away used needles and syringes in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Portions of this document last updated: Feb. 01, 2024

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