Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding gums
  3. blood in the urine or stools
  4. chest pain
  5. chills
  6. cough
  7. cracked lips
  8. decreased frequency or amount of urine
  9. diarrhea
  10. difficult or labored breathing
  11. difficulty in swallowing
  12. dry mouth
  13. fever
  14. headache
  15. hoarseness
  16. increased blood pressure
  17. increased thirst
  18. irregular heartbeat
  19. loss of appetite
  20. lower back or side pain
  21. mood changes
  22. muscle aches, pain, or cramps
  23. nausea
  24. numbness or tingling in the hands, feet, or lips
  25. painful or difficult urination
  26. pale skin
  27. peeling of the skin
  28. pinpoint red spots on the skin
  29. seizures
  30. sore throat
  31. sores, ulcers, or white spots on the lips, tongue, or inside the mouth
  32. stuffy or runny nose
  33. swelling of the face, fingers, or lower legs
  34. swollen glands
  35. tightness in the chest
  36. troubled breathing
  37. troubled breathing with exertion
  38. unusual bleeding or bruising
  39. unusual tiredness or weakness
  40. vomiting
  41. weight gain

Less common

  1. Bladder pain
  2. bloody nose
  3. blurred vision
  4. body aches or pain
  5. burning or stinging of the skin
  6. cloudy urine
  7. dilated neck veins
  8. dizziness
  9. ear congestion
  10. extreme tiredness or weakness
  11. fainting
  12. fast, irregular, pounding, or racing heartbeat or pulse
  13. frequent urge to urinate
  14. general feeling of discomfort or illness
  15. irregular breathing
  16. joint pain
  17. loss of voice
  18. nasal congestion
  19. nervousness
  20. pain or tenderness around the eyes and cheekbones
  21. painful cold sores or blisters on the lips, nose, eyes, or genitals
  22. pounding in the ears
  23. shivering
  24. sneezing
  25. sweating
  26. trouble sleeping

Rare

  1. Chest discomfort
  2. hives, itching, skin rash
  3. joint stiffness or swelling
  4. neck tenderness or swelling
  5. redness of the skin
  6. tightness in the chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  2. difficulty in moving
  3. feeling of warmth
  4. muscle stiffness
  5. redness of the face, neck, arms and occasionally, upper chest
  6. sudden sweating

Less common

  1. Acne
  2. back pain
  3. belching
  4. bone pain
  5. constipation
  6. discoloration of the fingernails or toenails
  7. heartburn
  8. indigestion
  9. lack or loss of strength
  10. muscle spasm
  11. stomach upset or pain
  12. upper stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Feb. 01, 2023