Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Skin itching, blistering, or redness at the application site

Less common

  1. Blistering, burning, crusting, dryness, or flaking of the skin
  2. bloody or black, tarry stools
  3. burning feeling at the application site
  4. constipation
  5. difficult urination
  6. hardening or thickening of the skin under patch
  7. itching, scaling, severe redness, soreness, or swelling of the skin
  8. pelvic pain
  9. severe stomach pain
  10. vomiting of blood or material that looks like coffee grounds

Rare

  1. Bladder pain
  2. bloody or cloudy urine
  3. blurred vision
  4. difficult, burning, or painful urination
  5. dizziness
  6. frequent urge to urinate
  7. headache
  8. lower back or side pain
  9. nervousness
  10. pounding in the ears
  11. slow or fast heartbeat
  12. testicular problems

Incidence not known

  1. Pain, redness, or swelling in the arm or leg

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Discouragement
  2. feeling sad or empty
  3. irritability
  4. lack of appetite
  5. loss of interest or pleasure
  6. rash
  7. tiredness
  8. trouble concentrating
  9. trouble sleeping

Rare

  1. Accelerated growth
  2. blemishes on the skin
  3. body pain
  4. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  5. cold hands and feet
  6. contamination of the application site
  7. decreased interest in sexual intercourse
  8. fear
  9. feeling of constant movement of self or surroundings
  10. inability to have or keep an erection
  11. increased appetite
  12. lightheadedness
  13. loss in sexual ability, desire, drive, or performance
  14. loss of bladder control
  15. mood or mental changes
  16. pimples
  17. sensation of spinning
  18. thinking abnormalities
  19. weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Feb. 01, 2023

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