Description and Brand Names
Drug information provided by: Merative, Micromedex®
US Brand Name
- Hepatolite
Descriptions
Technetium Tc 99m disofenin injection is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents, which may be used to find and treat certain diseases or to study the function of the body's organs.
Technetium Tc 99m disofenin injection is used to help your doctor see an image of your liver, gallbladder, and bile duct to see how well they are working.
This medicine is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.
Before Using
In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of technetium Tc 99m disofenin injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Although appropriate studies on the relationship of age to the effects of technetium Tc 99m disofenin injection have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of technetium Tc 99m disofenin injection in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving technetium Tc 99m disofenin injection.
Breastfeeding
Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper Use
A doctor or other health professional will give you this medicine. This medicine is given through a needle placed in a vein.
It is best to receive this medicine without food, at least 4 hours before or after a meal.
Precautions
It is very important that your doctor check you closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.
This medicine may cause serious allergic reactions. Check with your doctor right away if you have a rash, itching, swelling of the face, tongue, and throat, trouble breathing, or chest pain after you get the injection.
You will be exposed to radiation when you are given this medicine. Talk with your doctor if you have concerns about this.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Rare
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Chills
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nausea
Incidence not known
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Blistering, peeling, or loosening of the skin
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cough
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diarrhea
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fever
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itching at the injection site
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joint or muscle pain
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red, irritated eyes
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sore throat
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sores, ulcers, or white spots in the mouth or on the lips
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unusual tiredness or weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Portions of this document last updated: Feb. 01, 2024
Original article: https://www.mayoclinic.org/drugs-supplements/technetium-tc-99m-disofenin-intravenous-route/side-effects/drg-20122631