Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. blistering, peeling, or loosening of the skin
  3. changes in skin color
  4. chest pain or tightness
  5. chills
  6. clay-colored stools
  7. cough or hoarseness
  8. dark urine
  9. diarrhea
  10. dizziness
  11. fever
  12. general feeling of tiredness or weakness
  13. headache
  14. itching, skin rash
  15. joint or muscle pain
  16. light-colored stools
  17. loss of appetite
  18. lower back or side pain
  19. nausea
  20. pain, tenderness, or swelling of the foot or leg
  21. painful or difficult urination
  22. pale skin
  23. red skin lesions, often with a purple center
  24. red, irritated eyes
  25. sore throat
  26. sores, ulcers, or white spots in the mouth or on the lips
  27. stomach pain
  28. swollen or painful glands
  29. trouble breathing
  30. unpleasant breath odor
  31. unusual bleeding or bruising
  32. vomiting of blood
  33. yellow eyes or skin

Incidence not known

  1. Back, leg, or stomach pains
  2. bleeding gums
  3. blindness or vision changes
  4. bloating
  5. blood in the urine or stools
  6. bluish-colored lips, fingernails, or palms
  7. burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings
  8. burning of the face or mouth
  9. cloudy urine
  10. clumsiness or unsteadiness
  11. confusion
  12. constipation
  13. continuing ringing or buzzing or other unexplained noise in the ears
  14. cracks in the skin
  15. decreased frequency or amount of urine
  16. difficulty with swallowing
  17. fainting spells
  18. fast, pounding, or irregular heartbeat or pulse
  19. general body swelling
  20. general feeling of discomfort or illness
  21. hair loss
  22. hearing loss
  23. hives
  24. increased thirst
  25. indigestion
  26. large, flat, blue, or purplish patches in the skin
  27. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  28. loss of heat from the body
  29. muscle or joint pain
  30. nosebleeds
  31. not able to pass urine
  32. numbness or tingling in the hands, feet, or lips
  33. pain or burning while urinating
  34. pinpoint red spots on the skin
  35. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  36. raised red swellings on the skin, the buttocks, legs, or ankles
  37. redness of the white part of the eyes
  38. redness, swelling, or soreness of the tongue
  39. seizures
  40. soreness of the muscles
  41. stiff neck or back
  42. stomach tenderness
  43. swelling of the face, hands, legs, and feet
  44. unsteadiness, trembling, or other problems with muscle control or coordination
  45. weakness in the hands or feet
  46. weakness or heaviness of the legs
  47. weight gain or loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Passing of gas

Incidence not known

  1. Discouragement
  2. feeling of constant movement of self or surroundings
  3. feeling sad or empty
  4. increased sensitivity of the skin to sunlight
  5. lack of feeling or emotion
  6. loss of interest or pleasure
  7. muscle pain, stiffness, cramps, or spasms
  8. nervousness
  9. redness or other discoloration of the skin
  10. seeing, hearing, or feeling things that are not there
  11. sensation of spinning
  12. severe sunburn
  13. trouble concentrating
  14. trouble sleeping
  15. uncaring
  16. weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: Sept. 01, 2023