Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Accumulation of pus
  2. anxiousness, unexplained
  3. backache
  4. black or red, tarry stools
  5. bleeding from the gums or nose
  6. blurred vision
  7. body aches or pain
  8. bone pain
  9. bruising
  10. burning or stinging of the skin
  11. burning while urinating
  12. burning, dry, or itching eyes
  13. burning, tingling, numbness, or pain in the hands, arms, feet, or legs
  14. change in mental status
  15. changes in skin color
  16. chest pain
  17. chills
  18. confusion
  19. cough
  20. dark or bloody urine
  21. deafness
  22. decreased urine output
  23. decreased vision
  24. difficulty with breathing or swallowing
  25. dilated neck veins
  26. discharge from the eyes
  27. dizziness
  28. drowsiness
  29. dry mouth
  30. earache
  31. excessive tearing
  32. eye pain
  33. facial hair growth in females
  34. faintness or lightheadedness when getting up from lying or sitting position
  35. fast, slow, or irregular heartbeat
  36. fever
  37. flushing or redness of the skin, especially on the face and neck
  38. general feeling of discomfort or illness
  39. increased hunger
  40. increased menstrual flow or vaginal bleeding
  41. itching, pain, redness, swelling, tenderness, or warmth on the skin
  42. lack or loss of appetite
  43. large, flat, blue, or purplish patches in the skin
  44. loss of sexual ability, desire, drive, or performance
  45. loss of voice
  46. muscle pain
  47. nasal congestion
  48. nausea or vomiting
  49. numbness or tingling around the lips, hands, or feet
  50. pain in the chest, groin, or legs, especially the calves
  51. painful cold sores or blisters on the lips, nose, eyes, or genitals
  52. pale skin
  53. prolonged bleeding from cuts
  54. rapid heartbeat
  55. rash
  56. red or dark brown urine
  57. redness or swelling in the ear
  58. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  59. ringing in the ears
  60. runny nose
  61. seizures
  62. sensation of pins and needles
  63. severe constipation
  64. severe vomiting
  65. severe, sudden headache
  66. slurred speech
  67. sore throat
  68. sores or white spots on the lips or in the mouth
  69. stomach cramps, pain, or upset
  70. sudden decrease in the amount of urine
  71. sudden loss of coordination
  72. sudden, severe weakness or numbness in the arm or leg
  73. sweating
  74. swollen, painful, or tender lymph glands in the neck, armpit, or groin
  75. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area
  76. tremor
  77. ulcers on the lips or in the mouth
  78. unusual tiredness or weakness
  79. vision changes
  80. weakness or heaviness of the legs
  81. white patches in the mouth or on the tongue
  82. yellow skin and eyes

Less common

  1. Bloating
  2. change in size, shape, or color of existing mole
  3. hoarseness
  4. mole that leaks fluid or bleeds
  5. new mole
  6. pains in the stomach, side or abdomen, possibly radiating to the back
  7. skin ulcer or sores

Incidence not known

  1. Abnormal wound healing
  2. headache
  3. hives or itching
  4. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  5. nails loose or detached
  6. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  7. swelling of the arms or legs
  8. yellow nails lacking a cuticle

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Abnormal vision
  2. acne
  3. belching
  4. blistering, crusting, irritation, itching, or reddening of the skin
  5. burning feeling in the chest or stomach
  6. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feeling
  7. constipation
  8. continuing ringing or buzzing or other unexplained noise in the ears
  9. cracked, dry, or scaly skin
  10. crying
  11. decrease in frequency of urination
  12. degenerative disease of the joint
  13. depersonalization
  14. diarrhea
  15. difficulty with moving
  16. difficulty with passing urine (dribbling)
  17. dysphoria
  18. ear pain
  19. enlarged abdomen or stomach
  20. euphoria
  21. excess air or gas in the stomach or intestines
  22. excessive muscle tone, muscle tension or tightness
  23. fear
  24. feeling sad or empty
  25. hearing loss
  26. heartburn
  27. inability to have or keep an erection
  28. increase in heart rate
  29. increased hair growth, especially on the face
  30. increased urge to urinate during the night
  31. indigestion
  32. irritation in the mouth
  33. joint pain or swelling
  34. leg cramps
  35. loss of bladder control
  36. loss of energy or weakness
  37. loss of interest or pleasure
  38. loss of strength
  39. lower abdominal or stomach pain
  40. muscle aches, pain, stiffness, or weakness
  41. nervousness
  42. pain in the back, ribs, arms, or legs
  43. pain or burning in the throat
  44. pain or tenderness around the eyes and cheekbones
  45. paranoia
  46. pelvic pain
  47. quick to react or overreact emotionally
  48. rapid breathing
  49. rapidly changing moods
  50. inflammation, redness, or swelling of the gums or mouth
  51. shaking or trembling
  52. shivering
  53. sleepiness
  54. sunken eyes
  55. swelling
  56. swelling of the scrotum
  57. tender or enlarged gums
  58. tenderness in the stomach area
  59. thickening of the skin
  60. trouble concentrating
  61. trouble sleeping
  62. waking to urinate at night

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: Sept. 01, 2024

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