Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Blurred vision
  2. chest pain or discomfort
  3. confusion
  4. difficult or troubled breathing
  5. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  6. irregular, fast or slow, or shallow breathing
  7. lightheadedness, dizziness, or fainting
  8. muscle stiffness or tightness
  9. pale or blue lips, fingernails, or skin
  10. shortness of breath
  11. slow or irregular heartbeat
  12. sweating
  13. unusual tiredness or weakness

Less common

  1. Bluish lips or skin
  2. chills
  3. decrease in cardiac output
  4. fast, pounding, or heartbeat or pulse
  5. feeling of warmth
  6. fever
  7. headache
  8. nausea or vomiting
  9. nervousness
  10. not breathing
  11. pain after surgery
  12. pain in the shoulders, arms, jaw, or neck
  13. pounding in the ears
  14. problems with bleeding or clotting
  15. redness of the face, neck, arms, and occasionally, upper chest
  16. shivering


  1. Abdominal or stomach pain
  2. black, tarry stools
  3. bleeding gums
  4. blood in the urine or stools
  5. body aches or pain
  6. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  7. congestion
  8. cough or hoarseness
  9. cough producing mucus
  10. coughing that sometimes produces a pink frothy sputum
  11. coughing up blood
  12. decreased frequency or amount of urine
  13. difficult, fast, or noisy breathing
  14. difficulty with swallowing
  15. disorientation
  16. dry mouth
  17. dryness or soreness of the throat
  18. dysphoria
  19. eye pain
  20. flushed, dry skin
  21. fruit-like breath odor
  22. general feeling of illness
  23. hiccups
  24. hives, itching, or skin rash
  25. increased blood pressure
  26. increased hunger
  27. increased menstrual flow or vaginal bleeding
  28. increased sweating
  29. increased thirst
  30. increased urination
  31. loss of appetite
  32. lower back or side pain
  33. muscle cramps or pain
  34. nervousness
  35. noisy breathing
  36. nosebleeds
  37. numbness or tingling in the hands, feet, or lips
  38. painful or difficult urination
  39. pale skin
  40. paralysis
  41. pinpoint red spots on the skin
  42. prolonged bleeding from cuts
  43. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  44. rapid heartbeat
  45. red or black, tarry stools
  46. red or dark brown urine
  47. runny nose
  48. seizures
  49. shakiness in the legs, arms, hands, or feet
  50. small clicking, bubbling, or rattling sounds in the lungs when listening with a stethoscope
  51. stuffy nose
  52. swelling in the legs and ankles
  53. swelling of the face, fingers, or lower legs
  54. tender, swollen glands in the neck
  55. tightness in the chest
  56. troubled breathing with exertion
  57. unexplained weight loss
  58. unusual bleeding or bruising
  59. voice changes
  60. vomiting
  61. weakness and heaviness of the legs
  62. weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Anxiety
  2. blurred or loss of vision
  3. difficulty having a bowel movement (stool)
  4. disturbed color perception
  5. double vision
  6. halos around lights
  7. hyperventilation
  8. night blindness
  9. overbright appearance of lights
  10. pain at the injection site
  11. restlessness
  12. trouble with sleeping
  13. tunnel vision


  1. Burning while urinating
  2. heartburn
  3. hives or welts
  4. loss of bladder control
  5. loss of memory
  6. nightmares
  7. problems with memory
  8. seeing, hearing, or feeling things that are not there
  9. severe constipation
  10. severe vomiting
  11. trouble with urinating
  12. uncontrolled eye movements

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.