Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Cracked lips
  2. diarrhea
  3. difficulty with swallowing
  4. sores, ulcers, or white spots on the lips, tongue, or inside the mouth

Less common

  1. Abdominal or stomach pain
  2. agitation
  3. black or red, tarry, stools
  4. bleeding gums
  5. bluish color of the fingernails, lips, skin, palms, or nail beds
  6. changes in skin color
  7. changes in vision
  8. chest pain or discomfort
  9. chills
  10. coma
  11. confusion
  12. convulsions (seizures)
  13. cough
  14. coughing that sometimes produces a pink, frothy sputum
  15. coughing up blood
  16. decreased urination
  17. depression
  18. dilated neck veins
  19. dizziness
  20. dry mouth
  21. fainting
  22. fast, slow, or irregular heartbeat
  23. fever
  24. headache
  25. hostility
  26. increased menstrual flow or vaginal bleeding
  27. increased sweating
  28. increased thirst
  29. irritability
  30. itching, pain, redness, swelling, tenderness, or warmth on the skin
  31. lightheadedness
  32. lower back or side pain
  33. muscle twitching
  34. nausea
  35. no blood pressure or pulse
  36. nosebleeds
  37. pain or discomfort in the arms, jaw, back, or neck
  38. pain, tenderness, or swelling of the foot or leg
  39. painful or difficult urination
  40. pains in the chest, groin, or legs, especially calves of the legs
  41. pale skin
  42. paralysis
  43. prolonged bleeding from cuts
  44. red or dark brown urine
  45. severe constipation
  46. severe headaches of sudden onset
  47. shortness of breath
  48. skin rash
  49. sneezing
  50. sore throat
  51. stopping of heart
  52. stupor
  53. sudden loss of coordination
  54. sudden onset of shortness of breath for no apparent reason
  55. sudden onset of slurred speech
  56. sunken eyes
  57. sweating
  58. swelling of the face, fingers, feet, or lower legs
  59. swollen glands
  60. temporary blindness
  61. thirst
  62. tightness in the chest
  63. troubled breathing
  64. unconsciousness
  65. unexplained or unusual bleeding or bruising
  66. unusual tiredness or weakness
  67. vomiting
  68. weight gain
  69. wheezing
  70. wrinkled skin


  1. Back pain
  2. hives
  3. itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  4. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  2. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  3. feeling of warmth
  4. feeling unusually cold
  5. redness of the face, neck, arms, and occasionally, upper chest
  6. shivering

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.