Proper Use

Drug information provided by: IBM Micromedex

Peginesatide injection is usually given by a doctor. However, medicines given by injection are sometimes used at home. If you will be using peginesatide at home, your doctor will teach you how the injections are to be given. Be sure you understand exactly how the medicine is to be injected.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

This medicine is available in 3 forms. You may use a single-use vial (glass container), single-use prefilled syringe, or multiple-use vials.

This medicine may be given as a shot under your skin or into a vein. If your doctor tells you to inject it a certain way, follow your doctor's instructions.

If you are giving this medicine at home:

  • Use a new needle, unopened vial, or syringe each time you inject your medicine.
  • Do not use more medicine or use it more often than your doctor tells you to.
  • You will be shown the body areas where this shot can be given.
  • Throw away used needles and syringes in a hard, closed container that the needles cannot poke through (puncture-resistant). Keep this container away from children and pets.

You might not use all of the medicine in each vial or syringe. Use single-use vial or syringe only one time. Do not save an open single-use vial or syringe. If the medicine in the vial or syringe has changed color, or if you see particles in it, do not use it.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For anemia from chronic kidney failure:
      • Adults—Dose is based on body weight and must be determined by your doctor. The starting dose is 0.04 milligram (mg) per kilogram (kg) of body weight injected into a vein or under the skin once a month. Your doctor may adjust the dose as needed.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Store unused portions of the medicine in multiple use vials in the refrigerator and throw away the medicine 28 days after its first use. Protect the medicine from light. Keep your medicine in the original package until you are ready to use it.