Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding gums
  3. blood in the urine or stools
  4. blurred vision
  5. chest pain
  6. confusion
  7. convulsions
  8. cough
  9. decreased urine
  10. dizziness
  11. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  12. drowsiness
  13. dry mouth
  14. fainting
  15. fast or irregular heartbeat
  16. fever or chills
  17. headache
  18. increased thirst
  19. lightheadedness
  20. loss of appetite
  21. muscle pain or cramps
  22. muscle spasms (tetany) or twitching
  23. nausea or vomiting
  24. nervousness
  25. numbness or tingling in the hands, feet, or lips
  26. pale skin
  27. pinpoint red spots on the skin
  28. pounding in the ears
  29. rapid, shallow breathing
  30. seizures
  31. slow heartbeat
  32. sneezing
  33. sore throat
  34. sweating
  35. tightness in the chest
  36. trembling
  37. troubled breathing
  38. troubled breathing with exertion
  39. unusual bleeding or bruising
  40. unusual tiredness or weakness

Less common

  1. Abdominal or stomach cramps or pain
  2. bladder pain
  3. blue lips, fingernails, or skin
  4. bone pain
  5. chest discomfort
  6. cloudy urine
  7. coma
  8. decreased urine output
  9. difficult or troubled breathing
  10. difficult, burning, or painful urination
  11. fast, pounding, or irregular heartbeat or pulse
  12. frequent urge to urinate
  13. headache
  14. irregular, fast or slow, or shallow breathing
  15. irritability
  16. lower back or side pain
  17. muscle cramps in the hands, arms, feet, legs, or face
  18. restlessness
  19. swelling
  20. swelling of the face, feet, lower legs, ankles, or hands
  21. weakness or heaviness of the legs


  1. Severe pain in the chest
  2. sudden onset of severe breathing difficulty

Incidence not known

  1. Arm, back, or jaw pain
  2. blistering, peeling, or loosening of the skin
  3. bloating or swelling of the face, arms, hands, lower legs, or feet
  4. chest tightness or heaviness
  5. constipation
  6. cough or hoarseness
  7. dark-colored urine
  8. diarrhea
  9. difficulty with swallowing
  10. fever with or without chills
  11. general body swelling
  12. general feeling of tiredness or weakness
  13. greatly decreased frequency of urination or amount of urine
  14. high fever
  15. hives or skin rash
  16. indigestion
  17. joint or muscle pain
  18. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  19. light-colored stools
  20. noisy breathing
  21. nosebleeds
  22. pain with swallowing
  23. pains in the stomach, side, or abdomen, possibly radiating to the back
  24. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  25. rapid weight gain
  26. red skin lesions, often with a purple center
  27. red, irritated eyes
  28. sores, ulcers, or white spots on the lips or in the mouth
  29. stomach pain, continuing
  30. sweating
  31. swollen glands
  32. unexplained bleeding or bruising
  33. unusual weight gain or loss
  34. weight gain
  35. yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Feeling of warmth
  2. increased sweating
  3. redness of the face, neck, arms, and occasionally, upper chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Agitation
  2. cold sweats
  3. cool, pale skin
  4. depression
  5. excess air or gas in the stomach or intestines
  6. flushed, dry skin
  7. fruit-like breath odor
  8. full feeling
  9. increased hunger
  10. increased thirst
  11. increased urination
  12. lack or loss of strength
  13. nightmares
  14. passing gas
  15. shakiness
  16. slurred speech
  17. white patches in the mouth or throat or on the tongue
  18. white patches with diaper rash

Incidence not known

  1. Abnormal dreams
  2. attack, assault, or force
  3. bad, unusual, or unpleasant (after) taste
  4. blindness
  5. blue-yellow color blindness
  6. change in taste
  7. continuing ringing or buzzing or other unexplained noise in the ears
  8. decreased vision
  9. double vision
  10. dry eyes or skin
  11. eye pain
  12. feeling of constant movement of self or surroundings
  13. general feeling of discomfort or illness
  14. hair loss or thinning of the hair
  15. hearing loss
  16. hives or welts
  17. increased sensitivity of the skin to sunlight
  18. itching, redness, tearing, or other sign of eye irritation not present before use of this medicine or becoming worse during use
  19. lack of feeling or emotion
  20. pain in the testes
  21. pinpoint red or purple spots on the skin
  22. redness or other discoloration of the skin
  23. seeing, hearing, or feeling things that are not there
  24. sensation of spinning
  25. severe sunburn
  26. sleepiness or unusual drowsiness
  27. sugar in the urine
  28. swelling of the breasts or breast soreness in both females and males
  29. swelling or inflammation of the mouth
  30. trouble sleeping
  31. uncaring

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.