Drug information provided by: IBM Micromedex

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, you must have a negative pregnancy test before you will be allowed to receive this medicine. Female patients should use an effective form of birth control during treatment and for at least 6 months after the last dose. Male patients who have female partners should use an effective form of birth control (eg, condom) during treatment and for at least 3 months after the last dose. If you think you have become pregnant while using this medicine, tell your doctor right away.

This medicine may cause vomiting, rash, decreased appetite, fever, and irritability in infants exposed to breast milk. Talk with your doctor if you have any concerns about this.

If you plan to have children, talk with your doctor before using this medicine. Some men using this medicine have become infertile (unable to have children).

Serious allergic reactions can occur with this medicine. Check with your doctor right away if you have blurred vision, confusion, dizziness, fast or slow heartbeat, faintness, or lightheadedness when getting up from a lying or sitting position suddenly, itching skin, skin rash, sweating, swelling of the arms, face, legs, lips, tongue, or throat, trouble breathing, unusual tiredness or weakness with this medicine.

Do not drink alcohol during treatment with this medicine.

This medicine may cause nausea and vomiting which can lead to decreased appetite and weight. Check you body weight every 14 days. Your doctor may change your dose if needed.

Nifurtimox may increase your risk for acute attacks of porphyria. Call your doctor right away if you have darkening of the urine, fluid-filled skin blisters, itching of the skin, light-colored stools, skin sensitivity to the sun, skin thinness, or yellow eyes or skin.

This medicine may cause muscle weakness or tremors. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.