Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Belching
  2. bruising
  3. chest tightness
  4. difficult or labored breathing
  5. feeling of indigestion
  6. headache
  7. itching skin
  8. large, flat, blue, or purplish patches in the skin
  9. pain in the chest below the breastbone
  10. skin eruptions
  11. stomach pain
  12. swelling

Less common

  1. Bloating
  2. bloody or black, tarry stools
  3. blurred or loss of vision
  4. burning upper stomach pain
  5. cloudy urine
  6. constipation
  7. decrease in urine output or decrease in urine-concentrating ability
  8. disturbed color perception
  9. double vision
  10. fast, irregular, pounding, or racing heartbeat or pulse
  11. halos around lights
  12. indigestion
  13. loss of appetite
  14. nausea or vomiting
  15. night blindness
  16. overbright appearance of lights
  17. pale skin
  18. pinpoint red or purple spots on the skin
  19. severe and continuing nausea
  20. severe stomach burning, cramping, or pain
  21. skin rash
  22. swelling or inflammation of the mouth
  23. trouble breathing
  24. tunnel vision
  25. unusual bleeding or bruising
  26. unusual tiredness or weakness
  27. vomiting of material that looks like coffee grounds
  28. weight loss

Rare

  1. Anxiety
  2. back or leg pains
  3. bleeding gums
  4. blindness
  5. blistering, peeling, or loosening of the skin
  6. blood in the urine or stools
  7. blue lips and fingernails
  8. canker sores
  9. change in the ability to see colors, especially blue or yellow
  10. chest pain or discomfort
  11. clay-colored stools
  12. cold sweats
  13. coma
  14. confusion
  15. cool, pale skin
  16. cough or hoarseness
  17. coughing that sometimes produces a pink frothy sputum
  18. cracks in the skin
  19. darkened urine
  20. decreased vision
  21. depression
  22. diarrhea
  23. difficult, burning, or painful urination
  24. difficult, fast, or noisy breathing
  25. difficulty with swallowing
  26. dilated neck veins
  27. dizziness
  28. dry cough
  29. dry mouth
  30. early appearance of redness, or swelling of the skin
  31. excess air or gas in the stomach
  32. eye pain
  33. fainting
  34. fever with or without chills
  35. fluid-filled skin blisters
  36. flushed, dry skin
  37. frequent urination
  38. fruit-like breath odor
  39. greatly decreased frequency of urination or amount of urine
  40. hair loss
  41. high fever
  42. hives
  43. increased hunger
  44. increased sensitivity of the skin to sunlight
  45. increased sweating
  46. increased thirst
  47. increased urination
  48. increased volume of pale, dilute urine
  49. irregular breathing
  50. joint or muscle pain
  51. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  52. late appearance of rash with or without weeping blisters that become crusted, especially in sun-exposed areas of skin, may extend to unexposed areas
  53. light-colored stools
  54. lightheadedness
  55. loss of heat from the body
  56. lower back or side pain
  57. nervousness
  58. nightmares
  59. no blood pressure
  60. no breathing
  61. no pulse
  62. nosebleeds
  63. numbness or tingling in the hands, feet, or lips
  64. pain in the ankles or knees
  65. pain or burning in the throat
  66. pain or discomfort in the arms, jaw, back, or neck
  67. painful, red lumps under the skin, mostly on the legs
  68. pains in the stomach, side, or abdomen, possibly radiating to the back
  69. pale or blue lips, fingernails, or skin
  70. pounding in the ears
  71. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  72. rapid, shallow breathing
  73. red, irritated eyes
  74. red skin lesions, often with a purple center
  75. red-green color blindness
  76. redness or other discoloration of the skin
  77. redness, swelling, or soreness of the tongue
  78. scaly skin
  79. seizures
  80. severe sunburn
  81. shakiness
  82. skin thinness
  83. slurred speech
  84. sneezing
  85. sore throat
  86. sores, ulcers, or white spots on the lips or tongue or inside the mouth
  87. sores, welting, or blisters
  88. spots on your skin resembling a blister or pimple
  89. stiff neck or back
  90. stomach cramps or tenderness
  91. stomach upset
  92. swelling in the legs and ankles
  93. swelling of the face, fingers, feet, or lower legs
  94. swollen, painful, or tender lymph glands in the neck, armpit, or groin
  95. tiny bumps on the inner lining of the eyelid
  96. unexplained weight loss
  97. unpleasant breath odor
  98. watery or bloody diarrhea
  99. weakness or heaviness of the legs
  100. weight gain
  101. yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Bleeding under the skin
  2. confusion about identity, place, and time
  3. muscle tremors
  4. restlessness
  5. sleepiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Continuing ringing or buzzing or other unexplained noise in the ears
  2. hearing loss

Less common

  1. Acid or sour stomach
  2. change in hearing
  3. feeling of constant movement of self or surroundings
  4. passing gas
  5. sensation of spinning
  6. stomach soreness or discomfort

Rare

  1. Appetite changes
  2. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  3. burning, dry, or itching eyes
  4. difficulty with moving
  5. discharge, excessive tearing
  6. general feeling of discomfort or illness
  7. lack or loss of strength
  8. menstrual changes
  9. muscle aching, cramping, stiffness, or weakness
  10. not able to concentrate
  11. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  12. seeing, hearing, or feeling things that are not there
  13. shakiness in the legs, arms, hands, or feet
  14. swollen joints
  15. trembling or shaking of the hands or feet
  16. trouble getting pregnant
  17. trouble performing routine tasks
  18. trouble sleeping
  19. unusual drowsiness, dullness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: July 01, 2023