Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Bladder pain
  2. bloody or cloudy urine
  3. chills
  4. cough
  5. diarrhea
  6. difficult, burning, or painful urination
  7. fever
  8. frequent urge to urinate
  9. general feeling of discomfort or illness
  10. headache
  11. hoarseness
  12. joint pain
  13. loss of appetite
  14. lower back or side pain
  15. muscle aches and pains
  16. nausea
  17. runny nose
  18. shivering
  19. sore throat
  20. sweating
  21. trouble sleeping
  22. unusual tiredness or weakness
  23. vomiting

Less common

  1. Blurred vision
  2. dizziness
  3. nervousness
  4. pounding in the ears
  5. slow or fast heartbeat


  1. Anxiety
  2. cold sweats
  3. confusion
  4. cool, pale skin
  5. depression
  6. hives or welts, itching, or skin rash
  7. increased hunger
  8. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  9. loss of consciousness
  10. nightmares
  11. redness of the skin
  12. seizures
  13. shakiness
  14. slurred speech

Incidence not known

  1. Agitation
  2. clay-colored stools
  3. confusion
  4. dark urine
  5. decreased awareness or responsiveness
  6. decreased urine output
  7. depression
  8. difficulty with swallowing
  9. hostility
  10. irritability
  11. muscle twitching
  12. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  13. rapid weight gain
  14. severe sleepiness
  15. swelling of the face, ankles, or hands
  16. tightness in the chest
  17. unpleasant breath odor
  18. vomiting of blood
  19. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Back pain
  2. belching
  3. body aches or pain
  4. constipation
  5. decreased appetite
  6. heartburn
  7. indigestion
  8. loss of voice
  9. pain or tenderness around the eyes and cheekbones
  10. sneezing
  11. stomach cramps, discomfort, or pain
  12. stuffy nose
  13. swollen mouth and tongue
  14. unpleasant taste
  15. urge to have bowel movement
  16. weight loss

Less common

  1. Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.