Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Decreased urine output
  2. dry mouth
  3. fever
  4. increased thirst
  5. irregular heartbeat
  6. loss of appetite
  7. mood changes
  8. muscle pain or cramps
  9. nausea
  10. numbness or tingling in the hands, feet, or lips
  11. seizures
  12. trouble breathing
  13. unusual tiredness or weakness
  14. vomiting

Less common

  1. Blurred vision
  2. chest pain
  3. chills
  4. clay-colored stools
  5. cloudy urine
  6. cold sweats
  7. confusion
  8. cough
  9. dark urine
  10. decrease in urine-concentrating ability
  11. diarrhea
  12. dizziness
  13. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  14. drowsiness
  15. feeling unusually cold
  16. headache
  17. itching, skin rash
  18. light-colored stools
  19. mental changes
  20. muscle cramps in the hands, arms, feet, legs, or face
  21. muscle spasms (tetany) or twitching
  22. nervousness
  23. noisy, rattling breathing
  24. numbness and tingling around the mouth or fingertips
  25. pounding in the ears
  26. shivering
  27. slow, fast, or pounding heartbeat or pulse
  28. sneezing
  29. sore throat
  30. stomach cramps or pain
  31. sweating
  32. swelling of the fingers, hands, feet, or lower legs
  33. tightness in the chest
  34. trembling
  35. trouble breathing at rest
  36. unpleasant breath odor
  37. vomiting of blood
  38. weight gain
  39. yellow eyes or skin


  1. Black, tarry stools
  2. bleeding gums
  3. blistering, peeling, or loosening of the skin
  4. bloating or swelling of the face, arms, hands, lower legs, or feet
  5. blood in the urine or stools
  6. blue lips and fingernails
  7. burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings
  8. continuing ringing or buzzing or other unexplained noise in the ears
  9. coughing that sometimes produces a pink frothy sputum
  10. cracks in the skin
  11. decreased appetite
  12. difficulty with swallowing
  13. dilated neck veins
  14. disturbed color perception
  15. double vision
  16. extreme tiredness or weakness
  17. fast or irregular breathing
  18. feeling of discomfort
  19. general feeling of tiredness or weakness
  20. halos around lights
  21. hearing loss
  22. hives or welts
  23. inflammation of the joints
  24. joint pain
  25. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  26. loss of heat from the body
  27. loss of vision
  28. lower back or side pain
  29. night blindness
  30. overbright appearance of lights
  31. painful or difficult urination
  32. pale skin
  33. pinpoint red spots on the skin
  34. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  35. rapid weight gain
  36. red skin lesions, often with a purple center
  37. red, irritated eyes
  38. red, swollen skin
  39. scaly skin
  40. sores, ulcers, or white spots on the lips or in the mouth
  41. stomach pain, continuing
  42. stomach tenderness
  43. swollen lymph glands
  44. tunnel vision
  45. unsteadiness or awkwardness
  46. unusual bleeding or bruising
  47. unusual weight gain or loss
  48. upper right abdominal or stomach pain
  49. weakness in the arms, hands, legs, or feet

Incidence not known

  1. Bloating
  2. constipation
  3. difficult, fast, noisy breathing
  4. indigestion
  5. loss of bladder control
  6. pains in the stomach, side, or abdomen, possibly radiating to the back

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Decreased interest in sexual intercourse
  2. difficulty having a bowel movement
  3. difficulty with moving
  4. discouragement
  5. feeling of constant movement of self or surroundings
  6. feeling sad or empty
  7. inability to have or keep an erection
  8. irritability
  9. loss in sexual ability, desire, drive, or performance
  10. loss of interest or pleasure
  11. muscle aching or stiffness
  12. pain or tenderness around the eyes and cheekbones
  13. passing of gas
  14. sensation of spinning
  15. sleepiness or unusual drowsiness
  16. soreness of the skin
  17. stomach fullness or discomfort
  18. stuffy or runny nose
  19. trouble concentrating
  20. trouble sleeping


  1. Belching
  2. change in taste
  3. hair loss or thinning of the hair
  4. heartburn
  5. increased need to urinate
  6. increased sensitivity of the eyes or skin to sunlight
  7. loss of taste
  8. menstrual changes
  9. passing urine more often
  10. redness or other discoloration of the skin
  11. severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.