Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:


  1. Arm, back, or jaw pain
  2. blood in the stools or urine
  3. blue lips and fingernails
  4. blurred vision
  5. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  6. bruising
  7. changes in skin color
  8. chest pain, discomfort, tightness, or heaviness
  9. confusion
  10. coughing
  11. coughing or vomiting blood
  12. coughing that sometimes produces a pink frothy sputum
  13. decrease in the frequency of urination
  14. decrease in urine volume
  15. difficult, fast, noisy breathing
  16. difficulty in passing urine (dribbling)
  17. difficulty with swallowing
  18. dizziness or lightheadedness
  19. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  20. fainting
  21. feeling of constant movement of self or surroundings
  22. headache
  23. hives, itching, or skin rash
  24. hoarseness
  25. increased sweating
  26. nausea
  27. nervousness
  28. painful urination
  29. pains in the chest, groin, or legs, especially calves of the legs
  30. pain, tenderness, or swelling of the foot or leg
  31. pale skin
  32. persistent bleeding or oozing from the puncture sites, mouth, or nose
  33. pounding in the ears
  34. rapid weight gain
  35. redness of the skin
  36. seizures
  37. sensation of spinning
  38. severe headaches of sudden onset
  39. severe numbness, especially on one side of the face or body
  40. slow, fast, or irregular heartbeat
  41. slow or irregular breathing
  42. stupor
  43. sudden loss of coordination
  44. sudden onset of slurred speech
  45. sudden vision changes
  46. sweating
  47. swelling around the eyes
  48. swelling in the legs and ankles
  49. unusual tiredness or weakness

Incidence not known

  1. Agitation
  2. black, tarry stools
  3. bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  4. blistering, peeling, or loosening of the skin
  5. chills
  6. coma
  7. confusion
  8. depressed mood
  9. depression
  10. diarrhea
  11. dry skin and hair
  12. extremely high fever or body temperature
  13. fast, shallow breathing
  14. fast, weak heartbeat
  15. feeling cold
  16. fever
  17. hair loss
  18. hoarseness or husky voice
  19. hostility
  20. irritability
  21. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  22. lethargy
  23. muscle cramps, stiffness, or twitching
  24. no sensation in the legs
  25. not able to pass urine
  26. pale, clammy skin
  27. red, irritated eyes
  28. sensitivity to heat
  29. sore throat
  30. sores, ulcers, or white spots in the mouth or on the lips
  31. swollen glands
  32. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
  33. thirst
  34. trouble sleeping
  35. unable to move the legs
  36. unusual bleeding or bruising
  37. weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Collection of blood under the skin
  2. deep, dark purple bruise
  3. dry mouth
  4. ringing in the ears
  5. vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.