Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Back pain
  2. bladder pain
  3. bloating or swelling of the face, arms, hands, lower legs, or feet
  4. bloody or black, tarry stools
  5. bloody or cloudy urine
  6. blurred vision
  7. body aches or pain
  8. chest pain or tightness
  9. chills
  10. confusion
  11. cough
  12. decreased frequency or amount of urine
  13. difficult, burning, or painful urination
  14. dizziness or lightheadedness
  15. drowsiness
  16. dry mouth
  17. fainting
  18. fast or irregular heartbeat
  19. fever
  20. frequent urge to urinate
  21. headache
  22. hoarseness
  23. increased thirst
  24. irregular heartbeat
  25. itching
  26. loss of appetite
  27. lower back or side pain
  28. nausea
  29. rapid weight gain
  30. seizures
  31. severe headache
  32. severe stomach pain
  33. sore throat
  34. tingling of the hands or feet
  35. trouble breathing
  36. ulcers, sores, or white spots in the mouth
  37. unusual bleeding or bruising
  38. unusual tiredness or weakness
  39. unusual weight gain or loss
  40. vomiting
  41. vomiting of blood or material that looks like coffee grounds
  42. wrinkled skin

Less common

  1. Persistent non-healing sore
  2. pink skin growth
  3. reddish skin patch or irritated area
  4. shiny skin bump
  5. white, yellow or waxy scar-like area on the skin

Incidence not known

  1. Blistering, peeling, or loosening of the skin
  2. dark urine
  3. diarrhea
  4. dilated neck veins
  5. difficulty swallowing
  6. general feeling of tiredness or weakness
  7. hives, skin rash
  8. joint pain, stiffness, or swelling
  9. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  10. light-colored stools
  11. muscle pain
  12. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  13. red skin lesions, often with a purple center
  14. red, irritated eyes
  15. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Belching
  2. decreased appetite
  3. difficulty having a bowel movement
  4. heartburn or indigestion
  5. indigestion
  6. lack or loss of strength
  7. muscle stiffness or spasms
  8. small red or purple spots on the skin
  9. stomach discomfort, upset, or pain
  10. swelling or inflammation of the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.

Portions of this document last updated: Sept. 01, 2023