Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Abdominal or stomach pain
  2. arm, back, or jaw pain
  3. bladder pain
  4. bleeding gums
  5. bloating or swelling of the face, arms, hands, lower legs, or feet
  6. bloody or cloudy urine
  7. blurred vision
  8. changes in skin color
  9. chest congestion
  10. chest pain or discomfort
  11. chest tightness or heaviness
  12. chills
  13. cold hands and feet
  14. confusion
  15. constipation
  16. convulsions
  17. cough or hoarseness
  18. coughing up blood
  19. decreased urine
  20. depression
  21. diarrhea
  22. difficult, burning, or painful urination
  23. difficulty with breathing or swallowing
  24. dilated neck veins
  25. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  26. dry mouth
  27. extreme fatigue
  28. fast, pounding, or irregular heartbeat or pulse
  29. feeling of warmth
  30. fever
  31. headache
  32. incoherent speech
  33. increased menstrual flow or vaginal bleeding
  34. increased thirst
  35. increased urination
  36. local infection at the catheter site
  37. loss of appetite
  38. metallic taste
  39. muscle pain or cramps
  40. muscle weakness
  41. nausea or vomiting
  42. nosebleeds
  43. numbness or tingling in the hands, feet, or lips
  44. pain at the injection site
  45. pain, redness, or swelling in the arm or leg
  46. paleness of the skin
  47. prolonged bleeding from cuts
  48. rapid weight gain
  49. red or black, tarry stools
  50. redness of the face, neck, arms, and occasionally, upper chest
  51. sweating
  52. swelling of the face, fingers, feet, or lower legs
  53. tightness in the chest
  54. tingling of the hands or feet
  55. unusual tiredness or weakness
  56. weight gain or loss

Less common

  1. Altered or abnormal touch sensation or sensitivity
  2. blue lips and fingernails
  3. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  4. coughing that sometimes produces a pink frothy sputum
  5. difficult, fast, or noisy breathing
  6. inability to speak
  7. increased sweating
  8. numbness or tingling in the hands, feet, or lips
  9. pain or discomfort in the arms, jaw, back, or neck
  10. seizures
  11. severe or sudden headache
  12. severe pain in the chest
  13. slurred speech
  14. sudden onset of severe breathing
  15. temporary blindness
  16. weakness in the arm or leg on one side of the body, sudden and severe
  17. weakness or heaviness of the legs

Incidence not known

  1. Feeling of fullness
  2. high fever
  3. pinpoint red spots on the skin
  4. sensitivity to heat
  5. sores, ulcers, or white spots on the lips or in the mouth
  6. swollen glands
  7. trouble sleeping
  8. troubled breathing with exertion

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Change in vision
  2. difficulty having a bowel movement (stool)
  3. difficulty with moving
  4. heartburn
  5. hives or welts
  6. impaired vision
  7. itching
  8. joint pain
  9. lack of appetite
  10. lack or loss of strength
  11. loss of interest or pleasure
  12. muscle pains or stiffness
  13. redness of the skin
  14. shakiness in the legs, arms, hands, or feet
  15. skin rash, encrusted, scaly and oozing
  16. sores on the skin
  17. swollen joints
  18. tiredness
  19. trembling or shaking of the hands or feet
  20. trouble concentrating

Less common

  1. Acid or sour stomach
  2. belching
  3. blurred vision or other changes in vision
  4. excess air or gas in the stomach or intestines
  5. indigestion
  6. leg cramps
  7. passing gas
  8. sleepiness or unusual drowsiness
  9. stomach discomfort or upset

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Feb. 01, 2021

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