Side Effects

Drug information provided by: Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Burning, numbness, tingling, or pain in the arms, hands, legs, or feet
  2. swelling of the stomach, face, fingers, hands, feet, or lower legs
  3. unusual tiredness or weakness
  4. weight gain

Less common

  1. Black, tarry stools
  2. blood in the urine or stools
  3. cough or hoarseness (accompanied by fever or chills)
  4. difficult or labored breathing
  5. difficult or painful urination (accompanied by fever or chills)
  6. difficulty with swallowing
  7. dizziness
  8. fast heartbeat
  9. fever or chills
  10. hives or skin rash
  11. itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  12. lower back or side pain (accompanied by fever or chills)
  13. noisy, rattling breathing
  14. pinpoint red spots on the skin
  15. red, scaly, swollen, or peeling areas of the skin (severe)
  16. tightness in the chest
  17. troubled breathing while at rest
  18. unusual bleeding or bruising


  1. Chest pain or discomfort
  2. decreased blood pressure
  3. fast or irregular heartbeat
  4. increased blood pressure

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Congestion
  2. diarrhea
  3. dryness or soreness of the throat
  4. nausea
  5. skin rash or redness (mild)
  6. sores or ulcers on the lips or tongue or inside the mouth
  7. weakness in the arms, hands, legs, or feet

Less common

  1. Bloody nose
  2. body aches or pain
  3. change in the color of the fingernails or toenails
  4. dry, red, hot, or irritated skin at the injection site
  5. headache
  6. hoarseness
  7. loosening or loss of the fingernails or toenails, sometimes painful
  8. pain in the joints or muscles
  9. pain, swelling, or lump under the skin at the injection site
  10. runny nose
  11. tender, swollen glands in the neck
  12. voice changes
  13. vomiting

incidence not known

  1. Burning, dry, or itching eyes
  2. burning upper abdominal or stomach pain
  3. confusion
  4. difficulty having a bowel movement (stool)
  5. discharge from the eyes
  6. excessive tearing
  7. pain and redness of the skin at the place of earlier radiation treatment
  8. rapid breathing
  9. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  10. sunken eyes
  11. tearing of the eyes
  12. wrinkled skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.