Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Acid or sour stomach
  2. belching
  3. bleeding gums
  4. blood in the urine or stools
  5. bloody or black, tarry stools
  6. burning while urinating
  7. chest pain
  8. chills
  9. cough
  10. clay-colored stools
  11. cloudy urine
  12. constipation
  13. dark urine
  14. decrease in urine output or decrease in urine-concentrating ability
  15. diarrhea
  16. dizziness
  17. feeling of indigestion
  18. fever
  19. frequent urge to urinate
  20. headache
  21. heartburn
  22. increased bleeding time
  23. indigestion
  24. itching skin or rash
  25. light-colored stools
  26. loss of appetite
  27. nausea and vomiting
  28. pain in the chest below the breastbone
  29. painful or difficult urination
  30. pale skin
  31. pinpoint red spots on the skin
  32. stomach bloating, burning, cramping, discomfort, upset, or pain
  33. sore throat
  34. sores, ulcers, or white spots on the lips or in the mouth
  35. swelling or inflammation of the mouth
  36. swollen glands
  37. trouble breathing
  38. unpleasant breath odor
  39. unusual bleeding or bruising
  40. unusual tiredness or weakness
  41. upper right abdominal or stomach pain
  42. vomiting of blood or material that looks like coffee grounds
  43. weight loss
  44. yellow eyes and skin

Less common

  1. Blistering, peeling, loosening of the skin
  2. blurred vision
  3. burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings
  4. confusion
  5. change in consciousness
  6. discouragement
  7. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  8. feeling of constant movement of self or surroundings
  9. feeling sad or empty
  10. irritability
  11. joint or muscle pain
  12. lack of appetite
  13. lack or loss of strength
  14. loss of consciousness
  15. loss of interest or pleasure
  16. nervousness
  17. pain or discomfort in the arms, jaw, back, or neck
  18. pale or blue lips, fingernails, or skin
  19. red irritated eyes
  20. red skin lesions, often with a purple center
  21. redness, soreness, or itching skin
  22. sensation of spinning
  23. shakiness in the legs, arms, hands, or feet
  24. sleepiness or unusual drowsiness
  25. stiff neck or back
  26. trembling or shaking of the hands or feet
  27. trouble concentrating
  28. trouble sleeping

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Agitation
  2. blurred vision
  3. change in consciousness
  4. change in the ability to see colors, especially blue or yellow
  5. confusion
  6. depression
  7. difficult or trouble breathing
  8. hives
  9. hostility
  10. irregular, fast or slow, or shallow breathing
  11. irritability
  12. loss of consciousness
  13. muscle twitching
  14. nervousness
  15. pain or discomfort in the chest, upper stomach, or throat
  16. pale or blue lips, fingernails, or skin
  17. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  18. rapid weight gain
  19. seizures
  20. sleepiness
  21. slow or fast heartbeat
  22. stupor
  23. swelling of the face, ankles, or hands
  24. tightness in the chest
  25. trouble sleeping
  26. unusual drowsiness, dullness, or feeling of sluggishness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Bloated
  2. continuing ringing or buzzing or other unexplained noise in the ears
  3. difficulty in swallowing
  4. excess air or gas in the stomach or intestines
  5. hearing loss
  6. lack or loss of strength
  7. pain or burning in the throat
  8. passing gas

Less common

  1. Burning, dry or itching eyes
  2. discharge, excessive tearing
  3. hair loss, thinning of the hair
  4. increased sensitivity of the skin to sunlight
  5. pain in the arms or legs
  6. redness, pain, swelling of the eye, eyelid, or inner lining of eyelid
  7. redness or other discoloration of the skin
  8. severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: Sept. 01, 2023