Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. blurred vision
  3. chest pain
  4. chills
  5. clay colored stools
  6. cloudy urine
  7. cough
  8. dark urine
  9. decrease in urine output or decrease in urine-concentrating ability
  10. decreased appetite
  11. dizziness
  12. fever
  13. headache
  14. itching
  15. loss of appetite
  16. nausea and vomiting
  17. nervousness
  18. painful or difficult urination
  19. pounding in the ears
  20. shakiness in the legs, arms, hands, or feet
  21. skin rash
  22. slow or fast heartbeat
  23. sore throat
  24. sores, ulcers, or white spots on the lips or in the mouth
  25. stomach pain
  26. swelling of the feet or lower legs
  27. swollen glands
  28. trembling or shaking of the hands or feet
  29. trouble breathing
  30. unusual bleeding or bruising
  31. unusual tiredness or weakness
  32. yellow eyes or skin

Less common

  1. Bleeding gums
  2. blood in the urine
  3. blood in the vomit
  4. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  5. chest tightness
  6. difficulty swallowing
  7. hives
  8. pale skin
  9. pinpoint red spots on the skin
  10. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  11. seizures


  1. Bloating
  2. chest discomfort
  3. constipation
  4. darkened urine
  5. hoarseness
  6. indigestion
  7. lower back or side pain
  8. night sweats
  9. pain or discomfort in the arms, jaw, back, or neck
  10. pains in the stomach, side, or abdomen, possibly radiating to the back
  11. sweating
  12. vomiting of blood or material that looks like coffee grounds

Incidence not known

  1. Back pain
  2. drowsiness
  3. headache, severe and throbbing
  4. muscle spasms (tetany) or twitching

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Bleeding, tender, or enlarged gums
  2. blemishes on the skin
  3. increased hair growth, especially on the face
  4. pain or tenderness around the eyes and cheekbones
  5. pimples
  6. stomach discomfort
  7. stuffy or runny nose

Less common

  1. Brittle fingernails
  2. burning feeling in the chest or stomach
  3. burning, dry, or itching eyes
  4. continuing ringing or buzzing or other unexplained noise in the ears
  5. cramps
  6. discharge or excessive tearing
  7. feeling of warmth
  8. hearing loss
  9. redness of the face, neck, arms, and occasionally, upper chest
  10. redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  11. swelling of the breasts or breast soreness in both females and males
  12. weight loss


  1. Blurred or loss of vision
  2. discouragement
  3. disturbed color perception
  4. double vision
  5. fear or nervousness
  6. feeling sad or empty
  7. halos around lights
  8. irritability
  9. joint pain
  10. loss of interest or pleasure
  11. night blindness
  12. overbright appearance of lights
  13. tiredness
  14. trouble concentrating
  15. trouble sleeping
  16. tunnel vision
  17. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  18. weakness
  19. weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.