Drug information provided by: IBM Micromedex

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood tests will be needed to check for unwanted effects. Your doctor may decrease your dose if unwanted effects occur.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment and for 2 weeks after the last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

This medicine may cause fertility (ability to have children) problems in men or women. Talk to your doctor before using this medicine if you plan to have children.

Using this medicine may cause skin cancers (eg, cutaneous squamous cell carcinoma, basal cell carcinoma). Your doctor should check your skin before taking this medicine, every 2 months while taking this medicine, and for 6 months after you stop taking this medicine. Tell your doctor right away if you have a change in size or color of a mole, new wart, or reddish bump that bleeds or does not heal.

Avoid overexposing your skin to sunlight. Always use sunscreen or sun blocking lotions and wear protective clothing and hats. Tell your doctor if you have sun rash, skin irritation, painful and itchy skin that is hot to the touch, bumps or tiny papules, or thickened, dry, wrinkled skin

This medicine may increase your risk of bleeding. Tell your doctor right away if you have bleeding gums, red or black, tarry stools, red or dark brown urine, dizziness, headache, abdominal pain, or unusual vaginal bleeding while you are taking this medicine.

This medicine may cause cardiomyopathy (heart disease). Tell your doctor right away if you have persistent coughing or wheezing, chest pain, fast, irregular, or pounding heartbeat, swelling of the feet or lower legs, shortness of breath, or unusual tiredness or weakness.

Call your doctor right away if you have a severe skin rash (especially if it covers a large area of your body), acne, or redness, blisters, swelling, peeling, or tenderness of the hands or feet. These may be symptoms of a serious skin problem.

Check with your doctor right away if blurred vision, loss of vision, or any change in vision occurs during treatment. These could be symptoms of a serious eye problem. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, a loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem.

Rhabdomyolysis (severe muscle problem) may occur while receiving this medicine. Tell your doctor right away if you have dark-colored urine, fever, muscle cramps, spasms, or pain, or unusual tiredness or weakness.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.