Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Body aches or pain
  2. chills
  3. cough
  4. difficulty breathing
  5. discouragement
  6. dizziness
  7. ear congestion
  8. feeling sad or empty
  9. fever
  10. headache
  11. irritability
  12. lack of appetite
  13. loss of interest or pleasure
  14. loss of voice
  15. poor coordination
  16. runny or stuffy nose
  17. shakiness and unsteady walk
  18. sleepiness or unusual drowsiness
  19. sneezing
  20. sore throat
  21. tiredness
  22. trouble concentrating
  23. trouble sleeping
  24. unsteadiness, trembling, or other problems with muscle control or coordination
  25. unusual tiredness or weakness

Less common

  1. Being forgetful
  2. bladder pain
  3. bloody or cloudy urine
  4. change in speech
  5. decrease in frequency of urination
  6. diarrhea
  7. difficulty in passing urine
  8. difficult, burning, or painful urination
  9. frequent urge to urinate
  10. general feeling of discomfort or illness
  11. joint pain
  12. loss of appetite
  13. lower back or side pain
  14. mood or mental changes
  15. muscle aches and pains
  16. nausea
  17. nervousness
  18. problems in urination or increase in the amount of urine
  19. shivering
  20. slurred speech
  21. sore throat
  22. sweating
  23. trouble speaking
  24. vomiting


  1. Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  2. changes in skin color
  3. chest pain, discomfort, or tightness
  4. cold sweats
  5. colds
  6. confusion
  7. cough or hoarseness
  8. difficulty with sleeping
  9. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  10. excessive dreaming
  11. excessive muscle tone
  12. excitement
  13. falling
  14. fast, irregular, pounding, or racing heartbeat or pulse
  15. feeling mad
  16. feeling of unreality
  17. flu-like symptoms
  18. headache, severe and throbbing
  19. lack of feeling or emotion
  20. lack or loss of self-control
  21. muscle stiffness, tension, or tightness
  22. nightmares
  23. pain, inflammation, or swelling in the calves, shoulders, or hands
  24. pain or swelling in the arms or legs without any injury
  25. pain, tenderness, or swelling of the foot or leg
  26. partial or slight paralysis
  27. scaling
  28. sense of detachment from self or body
  29. shakiness in the legs, arms, hands, or feet
  30. skin rash
  31. swelling around the eyes
  32. swelling of the face, ankle, foot, or knees
  33. thoughts of killing oneself changes in behavior
  34. trembling or shaking of the hands or feet
  35. uncaring
  36. vision changes

Incidence not known

  1. Anxiety
  2. black, tarry stools
  3. bleeding gums
  4. blood in the urine or stools
  5. change in consciousness
  6. chest congestion
  7. difficulty with coordination
  8. double vision
  9. drowsiness
  10. dry mouth
  11. feeling that others are watching you or controlling your behavior
  12. feeling that others can hear your thoughts
  13. feeling, seeing, or hearing things that are not there
  14. hyperventilation
  15. irregular, fast, slow, or shallow breathing
  16. irregular, twisting uncontrolled movement of the face, hands, arms, or legs
  17. loss of interest or pleasure
  18. loss of memory
  19. loss of strength or energy
  20. loss of voice
  21. muscle weakness
  22. pale or blue lips, fingernails, or skin
  23. pinpoint red spots on the skin
  24. problems with memory
  25. restlessness
  26. severe mood or mental changes
  27. sores, ulcers, or white spots on the lips or in the mouth
  28. stomach pain or fullness
  29. swollen glands
  30. trouble breathing
  31. uncontrolled eye movements
  32. unusual behavior
  33. unusual bleeding or bruising
  34. unusual weakness
  35. vivid dreams
  36. weight loss or gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Agitation
  2. change in consciousness
  3. changes in patterns and rhythms of speech
  4. confusion
  5. loss of consciousness
  6. loss of strength or energy
  7. mood or mental changes
  8. nightmares
  9. shakiness and unsteady walk
  10. sleepiness or unusual drowsiness
  11. slurred speech
  12. talkativeness
  13. trouble speaking
  14. unsteadiness, trembling, or other problems with muscle control or coordination
  15. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  16. unusual excitement, nervousness, restlessness, or irritability
  17. unusual weak feeling

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Decreased interest in sexual intercourse
  2. difficulty with swallowing
  3. dryness or soreness of the throat
  4. heavy bleeding
  5. hives
  6. inability to have or keep an erection
  7. longer than usual time to ejaculation of semen
  8. loss in sexual ability, desire, drive, or performance
  9. pain or tenderness around the eyes and cheekbones
  10. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  11. voice changes


  1. Acid or sour stomach
  2. ankle, knee, or great toe joint pain
  3. belching
  4. bleeding after defecation
  5. blistering, burning, crusting, dryness, or flaking of the skin
  6. bloated
  7. blurred or loss of vision
  8. change in color perception
  9. cracks in the skin at the corners of the mouth
  10. decrease or change in vision
  11. difficulty moving
  12. double vision
  13. dryness of the eyes
  14. earache
  15. excess air or gas in stomach or intestines
  16. feeling of constant movement of self or surroundings
  17. feeling of warmth
  18. frequent bowel movements
  19. full feeling
  20. hair loss or thinning of the hair
  21. halos around lights
  22. heartburn
  23. increased watering of the mouth
  24. indigestion
  25. irregularities in menstruation
  26. itching in the genital or other skin areas
  27. itching, scaling, severe redness, soreness, or swelling of the skin
  28. joint stiffness or swelling
  29. leg or muscle cramps
  30. loss of taste
  31. night blindness
  32. nosebleeds
  33. overbright appearance of lights
  34. pain in the breasts or pelvic area
  35. pain in the leg, nape, or back
  36. passing gas
  37. red, sore eyes
  38. redness of the face, neck, arms, and occasionally, upper chest
  39. redness or swelling in the ear
  40. sensation of spinning
  41. smaller amount of semen ejaculated than usual
  42. sore on the edge of the eyelid
  43. soreness or redness around the fingernails and toenails
  44. stomach discomfort, upset, or pain
  45. thickening of the tongue
  46. thirst
  47. tooth disorder
  48. toothache
  49. tunnel vision
  50. twitching of the eyes
  51. uncomfortable swelling around the anus
  52. worsening of acne

Incidence not known

  1. Burning feeling in the chest or stomach
  2. difficulty having a bowel movement (stool)
  3. increased appetite
  4. increased hair growth, especially on the face
  5. increased in sexual ability, desire, drive, or performance
  6. increased interest in sexual intercourse
  7. sore gums
  8. tenderness in the stomach area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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