Side Effects

Drug information provided by: Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

  1. Black, tarry stools
  2. bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  3. chest pain
  4. chills
  5. cough
  6. fever
  7. painful or difficult urination
  8. sores, ulcers, or white spots on the lips or in the mouth
  9. suicidal thoughts
  10. unusual bleeding or bruising
  11. unusual tiredness or weakness


  1. Abdominal or stomach cramps or pain
  2. ankle, knee, or great toe joint pain
  3. arm, back, or jaw pain
  4. back or side pain
  5. blistering, peeling, or loosening of the skin
  6. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  7. change in walking and balance
  8. changes in skin color, pain, tenderness, or swelling of the foot or leg
  9. changes in urination
  10. chest tightness or heaviness
  11. cold, clammy, or pale skin
  12. convulsions
  13. cough or hoarseness
  14. darkening of the skin
  15. diarrhea, watery and severe, which may also be bloody
  16. difficulty with breathing, chewing, swallowing, or talking
  17. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  18. fainting
  19. fast, slow, irregular, pounding, or racing heartbeat or pulse
  20. flushing or redness of the skin, especially on the face and neck
  21. headache, severe and throbbing
  22. increased sensitivity of the skin to sunlight
  23. indigestion
  24. irregular heartbeats
  25. itching skin
  26. joint or muscle pain
  27. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  28. light-colored stools
  29. loss of ability to use or understand speech or language
  30. mood or mental changes
  31. muscle spasm or jerking of all extremities
  32. nausea and vomiting
  33. numbness of the hands
  34. pain in the ankles or knees
  35. pain or discomfort in the arms, jaw, back, or neck
  36. pounding in the ears
  37. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  38. red skin lesions, often with a purple center
  39. red, irritated eyes
  40. severe constipation
  41. severe sunburn
  42. severe vomiting
  43. shakiness in the legs, arms, hands, or feet
  44. small red or purple spots on the skin
  45. sudden shortness of breath or troubled breathing
  46. trouble concentrating
  47. trouble sleeping
  48. unsteadiness, trembling, or other problems with muscle control or coordination
  49. vomiting of blood
  50. yellow eyes and skin

Incidence not known

  1. Bone pain
  2. burning, numbness, tingling, or painful sensations
  3. confusion as to time, place, or person
  4. excessive muscle tone
  5. increased sensitivity to pain or touch
  6. inflammation of the joints
  7. rhythmic movement of muscles
  8. seeing, hearing, or feeling things that are not there

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Acid or sour stomach
  2. runny nose
  3. sneezing


  1. Continuing ringing or buzzing or other unexplained noise in the ears
  2. eye pain
  3. hearing loss
  4. loss of sense of smell
  5. swelling of the breasts or breast soreness in both females and males
  6. white patches in the mouth or on the tongue

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.