Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

  1. Black, tarry stools
  2. chest pain
  3. chills
  4. cough
  5. fever
  6. painful or difficult urination
  7. sores, ulcers, or white spots on the lips or in the mouth
  8. suicidal thoughts
  9. unusual bleeding or bruising
  10. unusual tiredness or weakness


  1. Ankle, knee, or great toe joint pain
  2. arm, back, or jaw pain
  3. back or side pain
  4. blistering, peeling, or loosening of the skin
  5. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  6. change in walking and balance
  7. changes in skin color, pain, tenderness, or swelling of the foot or leg
  8. changes in urination
  9. chest tightness or heaviness
  10. cold, clammy, or pale skin
  11. cough
  12. darkening of the skin
  13. diarrhea, watery and severe, which may also be bloody
  14. difficulty with breathing, chewing, swallowing, or talking
  15. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  16. fainting
  17. fast, slow, irregular, pounding, or racing heartbeat or pulse
  18. flushing or redness of the skin, especially on the face and neck
  19. headache, severe and throbbing
  20. hoarseness
  21. increased sensitivity of the skin to sunlight
  22. indigestion
  23. irregular heartbeat
  24. itching skin
  25. joint or muscle pain
  26. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  27. light-colored stools
  28. loss of ability to use or understand speech or language
  29. mood or mental changes
  30. muscle spasm or jerking of the legs or arms
  31. nausea
  32. numbness of the hands
  33. pain in the ankles or knees
  34. pain or discomfort in the arms, jaw, back, or neck
  35. pounding in the ears
  36. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  37. red skin lesions, often with a purple center
  38. red, irritated eyes
  39. seizures
  40. severe constipation
  41. severe sunburn
  42. severe vomiting
  43. shakiness in the legs, arms, hands, or feet
  44. small red or purple spots on the skin
  45. stomach cramps or pain
  46. trouble concentrating
  47. trouble sleeping
  48. unsteadiness, trembling, or other problems with muscle control or coordination
  49. vomiting
  50. vomiting of blood
  51. white patches in the mouth or on the tongue
  52. yellow eyes and skin

Incidence not known

  1. Bone pain
  2. confusion as to time, place, or person
  3. excessive muscle tone
  4. increased sensitivity to pain or touch
  5. rhythmic movement of muscles
  6. seeing, hearing, or feeling things that are not there
  7. swelling of the joints

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  2. runny nose
  3. sneezing


  1. Continuing ringing or buzzing or other unexplained noise in the ears
  2. eye pain
  3. hearing loss
  4. loss of sense of smell
  5. swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.