Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Diarrhea

Less common

  1. Headache


  1. Agitation
  2. black, tarry stools
  3. bleeding gums
  4. blood in the urine or stools
  5. bluish color
  6. changes in skin color
  7. chest pain
  8. chills
  9. confusion
  10. cough
  11. decreased awareness or responsiveness
  12. decreased urine
  13. dizziness
  14. dry mouth
  15. fever
  16. hostility
  17. increased thirst
  18. irregular heartbeat
  19. irritability
  20. loss of appetite
  21. loss of consciousness
  22. mood changes
  23. muscle pain, cramps, or twitching
  24. nausea
  25. numbness or tingling in the hands, feet, or lips
  26. painful or difficult urination
  27. pinpoint red spots on the skin
  28. rapid weight gain
  29. seizures
  30. severe sleepiness
  31. sore throat
  32. sores, ulcers, or white spots on the lips or in the mouth
  33. swelling of the face, ankles, hands, foot, or leg
  34. swollen glands
  35. tenderness
  36. unusual bleeding or bruising
  37. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  38. vomiting
  39. white patches in the mouth or throat or on the tongue

Incidence not known

  1. Back, leg, or stomach pains
  2. blistering, peeling, or loosening of the skin
  3. bloody or cloudy urine
  4. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  5. cough
  6. dark urine
  7. difficulty breathing
  8. difficulty swallowing
  9. fast heartbeat
  10. general body swelling
  11. general feeling of tiredness or weakness
  12. hives, itching, skin rash
  13. hoarseness
  14. joint pain
  15. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  16. lower back or side pain
  17. nosebleeds
  18. painful or difficult urination
  19. pale skin
  20. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  21. red, irritated eyes red skin lesions, often with a purple center
  22. tightness in the chest
  23. unusual weight gain
  24. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Difficulty having a bowel movement
  2. stomach pain


  1. Anxiety
  2. change in taste
  3. loss of taste
  4. redness of the skin

Incidence not known

  1. Collection of blood under the skin, deep, dark purple bruise, or itching, pain, or swelling of the skin at the injection site
  2. dry, red, hot, or irritated skin
  3. itching of the vagina or genital area
  4. pain during sexual intercourse
  5. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins at the injection site
  6. thick, white vaginal discharge with no odor or with a mild odor

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.