Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Diarrhea
  2. loose stools

Less common

  1. Change in the color, amount, or odor of vaginal discharge


  1. Abdominal or stomach cramps or tenderness
  2. black, tarry stools
  3. bladder pain
  4. bleeding gums
  5. bloating or swelling of the face, arms, hands, lower legs, or feet
  6. bloody nose
  7. bloody or cloudy urine
  8. blurred vision
  9. burning while urinating
  10. chest pain
  11. collection of blood under the skin
  12. confusion
  13. continuing ringing or buzzing or other unexplained noise in the ears
  14. cough or hoarseness
  15. cough producing mucus
  16. dark urine
  17. decreased urination
  18. decreased urine output
  19. deep, dark purple bruise
  20. diarrhea, watery and severe, which may also be bloody
  21. difficult or labored breathing
  22. difficult, burning, or painful urination
  23. difficulty with breathing or troubled breathing
  24. dilated neck veins
  25. dizziness
  26. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  27. dry mouth
  28. extreme fatigue
  29. fainting
  30. fast, irregular, pounding, or racing heartbeat or pulse
  31. feeling of warmth or heat
  32. fever or chills
  33. flushing or redness of the skin, especially on the face and neck
  34. frequent urge to urinate
  35. general body swelling
  36. headache
  37. hearing loss
  38. heavier menstrual periods
  39. increase in heart rate
  40. increased thirst
  41. increased urge to urinate during the night
  42. increased weight
  43. irregular breathing
  44. irregular heartbeat
  45. itching of the vagina or genital area
  46. itching, pain, redness, or swelling
  47. loss of appetite
  48. lower back or side pain
  49. nausea or vomiting
  50. nervousness
  51. noisy breathing
  52. nosebleeds
  53. pain
  54. pain during sexual intercourse
  55. pain or swelling of the treated skin
  56. pain or tenderness around the eyes and cheekbones
  57. pain, warmth, or burning in the fingers, toes, and legs
  58. pale skin
  59. pinpoint red spots on the skin
  60. pounding in the ears
  61. problems with vision or hearing
  62. rapid breathing
  63. rapid weight gain
  64. runny nose
  65. shortness of breath or troubled breathing
  66. skin rash
  67. slow or fast heartbeat
  68. sneezing
  69. sore throat
  70. sores, ulcers, or white spots on the lips or in the mouth
  71. stuffy or runny nose
  72. sunken eyes
  73. sweating
  74. swelling of the face, fingers, feet, or lower legs
  75. swelling or puffiness of the face
  76. swollen glands
  77. thick, white vaginal discharge with no odor or with a mild odor
  78. thirst
  79. tightness of the chest or wheezing
  80. tingling of the hands or feet
  81. troubled breathing
  82. troubled breathing with exertion
  83. unusual bleeding or bruising
  84. unusual tiredness or weakness
  85. unusual weight gain or loss
  86. waking to urinate at night
  87. weight gain
  88. wheezing
  89. wrinkled skin
  90. yellowing of the eyes or skin

Incidence not known

  1. Abdominal or stomach pain
  2. blistering, peeling, or loosening of the skin
  3. bloody, black, or tarry stools
  4. clay-colored stools
  5. feeling of discomfort
  6. fever with or without chills
  7. general feeling of tiredness or weakness
  8. high fever
  9. inflammation of the joints
  10. irritation or inflammation of the eyelid
  11. itching
  12. joint or muscle pain
  13. muscle aches
  14. rectal bleeding
  15. red skin lesions, often with a purple center
  16. red, irritated eyes
  17. seizures
  18. sudden decrease in the amount of urine
  19. swollen lymph glands
  20. swollen or painful glands
  21. unpleasant breath odor
  22. vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  1. Accumulation of pus
  2. acid or sour stomach
  3. ankle, knee, or great toe joint pain
  4. bad, unusual, or unpleasant (after) taste
  5. belching
  6. blemishes on the skin
  7. bloated or full feeling
  8. burning feeling in the chest or stomach
  9. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  10. change in taste
  11. constipation
  12. cracks in the skin
  13. decreased appetite
  14. difficulty with moving
  15. dry skin
  16. excess air or gas in the stomach or intestines
  17. fear or nervousness
  18. feeling of constant movement of self or surroundings
  19. frequent urge to defecate
  20. general feeling of discomfort or illness
  21. hair loss
  22. headache, severe and throbbing
  23. heartburn
  24. hives or welts
  25. increase in body movements
  26. increased sweating
  27. increased thirst
  28. indigestion
  29. irritation or soreness of the mouth
  30. joint stiffness or swelling
  31. lack or loss of strength
  32. loss of heat from the body
  33. lower back or side pain
  34. muscle aching or cramping
  35. muscle pains or stiffness
  36. passing of gas
  37. peeling of the skin
  38. pimples
  39. poor concentration
  40. pressure in the stomach
  41. red, sore eyes
  42. red, swollen skin
  43. redness of the skin
  44. scaly skin
  45. seeing, hearing, or feeling things that are not there
  46. sensation of spinning
  47. sleepiness or unusual drowsiness
  48. sleeplessness
  49. sore mouth or tongue
  50. soreness or redness around the fingernails and toenails
  51. stomach discomfort, upset, or pain
  52. stomach upset
  53. straining while passing stool
  54. swelling of the abdominal or stomach area
  55. swelling or inflammation of the mouth
  56. swollen, red, or tender area of infection
  57. trouble with sleeping
  58. unable to sleep
  59. white patches in the mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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