Side Effects

Drug information provided by: Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Bloating or swelling of the face, arms, hands, lower legs, or feet
  2. rapid weight gain
  3. swelling, burn, or blisters at the patch site
  4. tingling of the hands or feet
  5. unusual weight loss

Less common

  1. Bladder pain
  2. bloody or cloudy urine
  3. blurred vision
  4. body aches or pain
  5. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  6. chest pain
  7. chills
  8. cough producing mucus
  9. diarrhea
  10. difficult or labored breathing
  11. difficult, burning, or painful urination
  12. difficulty with moving
  13. dizziness
  14. ear congestion
  15. fever
  16. frequent urge to urinate
  17. general feeling of discomfort or illness
  18. headache
  19. increased sweating
  20. joint pain
  21. loss of appetite
  22. loss of voice
  23. lower back or side pain
  24. muscle aches and pains
  25. muscle stiffness
  26. nasal congestion
  27. nausea
  28. nervousness
  29. pain
  30. pain in the arms or legs
  31. pounding in the ears
  32. runny nose
  33. shakiness in the legs, arms, hands, or feet
  34. shivering
  35. slow or fast heartbeat
  36. sneezing
  37. sore throat
  38. sweating
  39. tightness in the chest
  40. trembling or shaking of the hands or feet
  41. trouble sleeping
  42. unusual tiredness or weakness
  43. vomiting


  1. Abdominal or stomach pain or tenderness
  2. arm, back, or jaw pain
  3. blistering, burning, crusting, dryness, or flaking of the skin
  4. blue lips, fingernails, or skin
  5. chest tightness or heaviness
  6. confusion
  7. decreased urination
  8. deep or fast breathing with dizziness
  9. difficulty with swallowing
  10. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  11. dry mouth
  12. extremely shallow or slow breathing
  13. fainting
  14. fast, irregular, pounding, or racing heartbeat or pulse
  15. feeling of warmth or heat
  16. flushing or redness of the skin, especially on the face and neck
  17. increase in heart rate
  18. irregular, fast or slow, or shallow breathing
  19. itching, scaling, severe redness, soreness, or swelling of the skin
  20. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  21. lightheadedness, dizziness, or fainting
  22. loss of bladder control
  23. loss of consciousness
  24. numbness of the feet, hands, and around the mouth
  25. rapid breathing
  26. slow or irregular heartbeat
  27. sunken eyes
  28. sweating
  29. swelling or puffiness of the face
  30. thirst
  31. trouble with walking
  32. wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Change in consciousness
  2. cold and clammy skin
  3. convulsions (seizures)
  4. drowsiness that is so severe you are not able to answer when spoken to or, if asleep, cannot be awakened
  5. pale or blue lips, fingernails, or skin
  6. pinpoint (small) pupils in the eyes
  7. sleepiness or unusual drowsiness
  8. slow heartbeat
  9. unable to speak
  10. very slow or troubled breathing
  11. weak muscle tone

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Constipation
  2. itching, redness, or rash at the patch site

Less common

  1. Acid or sour stomach
  2. anxiety
  3. back pain
  4. belching
  5. depression
  6. headache, severe and throbbing
  7. heartburn
  8. indigestion
  9. irritation at the patch site
  10. itching skin
  11. lack or loss of strength
  12. muscle spasms
  13. neck pain
  14. pain or tenderness around the eyes and cheekbones
  15. rash
  16. stomach discomfort, upset, or pain
  17. swelling of the joints
  18. upper abdominal or stomach pain
  19. weight loss


  1. Agitation
  2. being forgetful
  3. blurred or loss of vision
  4. change in taste
  5. changes in patterns and rhythms of speech
  6. clumsiness or unsteadiness
  7. confusion about identity, place, and time
  8. cramps
  9. decreased interest in sexual intercourse
  10. decreased weight
  11. disturbed color perception
  12. double vision
  13. dry eyes or skin
  14. excess air or gas in the stomach or intestines
  15. feeling of constant movement of self or surroundings
  16. feeling of unreality
  17. full feeling
  18. general feeling of discomfort or illness
  19. halos around lights
  20. heavy bleeding
  21. inability to have or keep an erection
  22. lack of feeling or emotion
  23. loss in sexual ability, desire, drive, or performance
  24. loss of taste
  25. muscle weakness
  26. night blindness
  27. nightmares
  28. overbright appearance of lights
  29. passing gas
  30. pressure in the stomach
  31. relaxed and calm
  32. restlessness
  33. sensation of spinning
  34. sense of detachment from self or body
  35. sleepiness
  36. slurred speech
  37. swelling of the abdominal or stomach area
  38. trouble with speaking
  39. tunnel vision
  40. uncaring

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.