Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Drowsiness
  2. relaxed and calm feeling
  3. sleepiness


  1. Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  2. bluish color of the fingernails, lips, skin, palms, or nail beds
  3. blurred vision
  4. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  5. chest pain, discomfort, or tightness
  6. confusion
  7. difficult or labored breathing
  8. feeling, seeing, or hearing things that are not there
  9. feeling that others are watching you or controlling your behavior
  10. feeling that others can hear your thoughts
  11. headache
  12. severe mood or mental changes
  13. slurred speech
  14. unusual behavior

Incidence not known

  1. Agitation
  2. anxiety
  3. chills
  4. cold sweats
  5. coma
  6. cool, pale skin
  7. cough
  8. darkening of the skin
  9. deep or fast breathing with dizziness
  10. diarrhea
  11. dizziness
  12. dry mouth
  13. fainting
  14. fever
  15. increased hunger
  16. increased sensitivity to pain
  17. irregular heartbeats
  18. irritability
  19. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  20. loss of appetite
  21. loss of muscle coordination
  22. nausea
  23. nervousness
  24. nightmares
  25. noisy breathing
  26. overactive reflexes
  27. poor coordination
  28. restlessness
  29. seizures
  30. shaking
  31. shivering
  32. skin rash
  33. sweating
  34. talking or acting with excitement which you cannot control
  35. trouble sleeping
  36. twitching
  37. unusual tiredness or weakness
  38. vomiting
  39. worsening of pain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Blurred vision
  2. confusion
  3. difficult or trouble breathing
  4. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  5. irregular, fast or slow, or shallow breathing
  6. pale or blue lips, fingernails, or skin
  7. pinpoint pupils
  8. relaxed and calm
  9. sleepiness or unusual drowsiness
  10. sweating
  11. unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Constricted, pinpoint, or small pupils (black part of the eye)
  2. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  3. extremely shallow or slow breathing
  4. sweating


  1. Burning, dry, or itching eyes
  2. continuing ringing or buzzing or other unexplained noise in the ears
  3. decrease in the frequency of urination
  4. decrease in urine volume
  5. depression
  6. difficulty in passing urine (dribbling)
  7. discharge, excessive tearing
  8. dreaming
  9. dry mouth
  10. false or unusual sense of well-being
  11. fast, pounding, or irregular heartbeat or pulse
  12. feeling of warmth
  13. hearing loss
  14. itching of the skin
  15. painful urination
  16. pounding in the ears
  17. redness of the face, neck, arms, and occasionally, upper chest
  18. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

Incidence not known

  1. Belching
  2. bloated
  3. bluish lips or skin
  4. change in vision
  5. excess air or gas in the stomach or intestines
  6. feeling of fullness
  7. feeling of unreality
  8. general feeling of discomfort or illness
  9. heartburn
  10. hives or welts
  11. impaired vision
  12. indigestion
  13. not breathing
  14. paleness of the skin
  15. passing gas
  16. redness of the skin
  17. sense of detachment from self or body
  18. stomach discomfort, upset, or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.