Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

1. Black, tarry stools
2. bladder pain
3. bloating or swelling of the face, arms, hands, lower legs, or feet
4. bloody or cloudy urine
5. blurred vision
6. body aches or pain
7. chest tightness
8. chills
9. constipation
10. cough
11. diarrhea
12. difficult, burning, or painful urination
13. difficulty in breathing
14. dizziness
15. ear congestion
16. fever
17. frequent urge to urinate
18. general feeling of tiredness and weakness
19. headache
20. hoarseness
21. loss of appetite
22. loss of voice
23. lower back or side pain
24. muscle aches
25. nausea
26. nervousness
27. nosebleed
28. pain
29. pale skin
30. pounding in the ears
31. rapid weight gain
32. slow or fast heartbeat
33. sneezing
34. sore throat
35. stomach cramps
36. stuffy or runny nose
37. tenderness
38. tingling of the hands or feet
39. ulcers, sores, or white spots in the mouth
40. unusual bleeding or bruising
41. unusual tiredness or weakness
42. unusual weight gain or loss
43. vomiting
44. watery or bloody diarrhea

Less common

1. Anxiety
2. burning, tingling, numbness or pain in the hands, arms, feet, or legs
3. chest pain
4. confusion
5. dark urine
6. decreased urine
7. depressed mood
8. difficulty with chewing, swallowing, or talking
9. double vision
10. drooping eyelids
11. drowsiness
12. dry skin and hair
13. facial swelling
14. feeling cold
15. general feeling of discomfort or illness
16. increased thirst
17. inability to move the arms and legs
18. irritability
19. light-colored stools
20. lightheadedness
21. muscle cramp, stiffness, or weakness
22. numbness in the hands, feet, or lips
23. rapid, shallow breathing
24. seizures
25. sensation of pins and needles
26. sensitivity to heat
27. skin rash
28. stabbing pain
29. stiff neck or back
30. sudden numbness and weakness in the arms and legs
31. sweating
32. swelling of the face, ankles, hands, or feet
33. thickening of bronchial secretions
34. trouble sleeping
35. upper right abdominal or stomach pain
36. yellow eyes and skin

Rare

1. Blistering, peeling, or loosening of the skin
2. darkening of the skin
3. fainting
4. hives, itching
5. indigestion
6. joint pain, stiffness, or swelling
7. muscle pain
8. pains in the stomach, side, or abdomen, possibly radiating to the back
9. red skin lesions, often with a purple center
10. red, irritated eyes
11. redness of the skin
12. swelling of the eyelids or lips
13. swollen glands

Incidence not known

1. Blue or pale skin
2. chest pain, possibly moving to the left arm, neck, or shoulder
3. flushed, dry skin
4. fruit-like breath odor
5. increased hunger
6. increased urination
7. trouble breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

1. Back, neck, arm, or leg pain
2. difficulty in moving
3. loss of or change in taste
4. thinning of the hair or hair loss
5. unsteadiness or awkwardness
6. weakness in the arms, hands, legs, or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: June 01, 2023

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