Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bladder pain
  3. bloating or swelling of the face, arms, hands, lower legs, or feet
  4. bloody or cloudy urine
  5. blurred vision
  6. body aches or pain
  7. chest tightness
  8. chills
  9. constipation
  10. cough
  11. diarrhea
  12. difficult, burning, or painful urination
  13. difficulty in breathing
  14. dizziness
  15. ear congestion
  16. fever
  17. frequent urge to urinate
  18. general feeling of tiredness and weakness
  19. headache
  20. hoarseness
  21. loss of appetite
  22. loss of voice
  23. lower back or side pain
  24. muscle aches
  25. nausea
  26. nervousness
  27. nosebleed
  28. pain
  29. pale skin
  30. pounding in the ears
  31. rapid weight gain
  32. slow or fast heartbeat
  33. sneezing
  34. sore throat
  35. stomach cramps
  36. stuffy or runny nose
  37. tenderness
  38. tingling of the hands or feet
  39. ulcers, sores, or white spots in the mouth
  40. unusual bleeding or bruising
  41. unusual tiredness or weakness
  42. unusual weight gain or loss
  43. vomiting
  44. watery or bloody diarrhea

Less common

  1. Anxiety
  2. burning, tingling, numbness or pain in the hands, arms, feet, or legs
  3. chest pain
  4. confusion
  5. dark urine
  6. decreased urine
  7. depressed mood
  8. difficulty with chewing, swallowing, or talking
  9. double vision
  10. drooping eyelids
  11. drowsiness
  12. dry skin and hair
  13. facial swelling
  14. feeling cold
  15. general feeling of discomfort or illness
  16. increased thirst
  17. inability to move the arms and legs
  18. irritability
  19. light-colored stools
  20. lightheadedness
  21. muscle cramp, stiffness, or weakness
  22. numbness in the hands, feet, or lips
  23. rapid, shallow breathing
  24. seizures
  25. sensation of pins and needles
  26. sensitivity to heat
  27. skin rash
  28. stabbing pain
  29. stiff neck or back
  30. sudden numbness and weakness in the arms and legs
  31. sweating
  32. swelling of the face, ankles, hands, or feet
  33. thickening of bronchial secretions
  34. trouble sleeping
  35. upper right abdominal or stomach pain
  36. yellow eyes and skin


  1. Blistering, peeling, or loosening of the skin
  2. darkening of the skin
  3. fainting
  4. hives, itching
  5. indigestion
  6. joint pain, stiffness, or swelling
  7. muscle pain
  8. pains in the stomach, side, or abdomen, possibly radiating to the back
  9. red skin lesions, often with a purple center
  10. red, irritated eyes
  11. redness of the skin
  12. swelling of the eyelids or lips
  13. swollen glands

Incidence not known

  1. Blue or pale skin
  2. chest pain, possibly moving to the left arm, neck, or shoulder
  3. flushed, dry skin
  4. fruit-like breath odor
  5. increased hunger
  6. increased urination
  7. trouble breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Back, neck, arm, or leg pain
  2. difficulty in moving
  3. loss of or change in taste
  4. thinning of the hair or hair loss
  5. unsteadiness or awkwardness
  6. weakness in the arms, hands, legs, or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.