Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Do not take this medicine together with alosetron (‎Lotronex®), dolasetron (Anzemet®), granisetron (Kytril®, Sancuso®), ondansetron (Ondisolv®, Zofran®), or palonosetron (Aloxi®).

Do not change your dose or stop using this medicine without first checking with your doctor. Stopping this medicine suddenly may cause fever, confusion, or severe muscle stiffness.

Call your doctor if your symptoms do not improve or if they get worse.

This medicine may make you dizzy or drowsy, or cause trouble with controlling body movements, which may lead to falls. It may also cause you to fall asleep without warning. This could happen while you are driving, eating, or talking. Tell your doctor right away if this happens. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Standing up slowly from a sitting or lying position can help prevent getting dizzy.

This medicine may cause serious allergic reactions, which an be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.

This medicine can cause swelling or inflammation of the mouth. Talk to your doctor if you have any concerns.

Some people who have used this medicine had unusual changes in their mood or behavior. Talk with your doctor right away if you start seeing, hearing, or feeling things that are not there, or start having unusual urges, such as gambling urges, binge or compulsive eating, compulsive shopping, or sexual urges while using this medicine.

Check with your doctor right away if you have back, leg, or stomach pains, bleeding gums, chills, dark urine, difficulty breathing, fever, general body swelling, headache, loss of appetite, nausea or vomiting, nosebleeds, pale skin, sore throat, unusual tiredness or weakness, or yellowing of the eyes or skin. These may be symptoms of a blood problem called hemolytic anemia.

This medicine may also increase your risk of having serious heart and blood vessel problems such as chest pain or heart attack. Check with your doctor right away if you start having chest pain or discomfort, pain or discomfort in the arms, jaw, back or neck, trouble breathing, nausea, sweating, or vomiting.

Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Make sure your doctor knows if you had a heart rhythm problem, such as QT prolongation.

This medicine may increase your risk for fibrotic complications (tissue changes in the pelvis, lungs, and heart valves). Check with your doctor right away if you have fever, general feeling of illness, loss of appetite, lower stomach or back pain, cough, or trouble breathing.

If you experience a prolonged or painful erection of the penis for more than 4 hours, check with your doctor right away.

Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). The use of alcohol or other medicines that affect the CNS with apomorphine may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.