Proper Use

Drug information provided by: Merative, Micromedex®

A doctor or other trained health professional will give you this medicine in a hospital or clinic setting. It is given through a needle placed into one of your veins. You may also be taught how to give this medicine at home.

To prepare the medicine using 1 vial and 1 prefilled syringe:

  • Take the vial and prefilled syringe out of the refrigerator and warm them to room temperature.
  • Wipe the rubber stopper with an alcohol swab and allow them to dry.
  • Peel the lid of the vial adapter. Keep the vial on a flat surface. Hold the vial with one hand and using the other hand, connect the syringe into the vial by pushing the tip onto the luer lock (tip) in the center of the vial, turn it clockwise until secured.
  • On a flat surface, place the vial adapter over the vial and push the filter spike of the adapter into the center of the vial's rubber until the clear plastic cap snaps into the vial.
  • Slowly push down on the plunger to inject all liquid from the syringe into the vial. Swirl the bottle gently to dissolve the medicine.
  • Check the mixture to make sure it is clear and colorless. Do not use the medicine if you can see particles in it.
  • Gently unscrew the syringe from the vial by turning it counter clockwise.
  • Give the injection as directed by your doctor.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (injection):
    • For bleeding episodes in patients with hemophilia A:
      • Adults—Dose is based on body weight and the type of bleeding episode. The dose must be determined by your doctor.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.


Store in the refrigerator. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Use the mixture within 3 hours after it is prepared. Throw away unused mixture within 3 hours after mixing.