Side Effects

Drug information provided by: Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Swelling of the ankles or feet

Less common

  1. Difficult or labored breathing
  2. dizziness
  3. fast, irregular, pounding, or racing heartbeat or pulse
  4. feeling of warmth
  5. redness of the face, neck, arms, and occasionally, upper chest
  6. shortness of breath
  7. tightness in the chest
  8. wheezing


  1. Black, tarry stools
  2. bleeding gums
  3. blistering, peeling, or loosening of the skin
  4. blood in the urine or stools
  5. blurred vision
  6. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  7. chest pain or discomfort
  8. chills
  9. cold and clammy skin
  10. cold sweats
  11. confusion
  12. dark yellow urine
  13. cough
  14. diarrhea
  15. dilated neck veins
  16. dizziness or lightheadedness when getting up from a lying or sitting position
  17. extra heartbeats
  18. extreme fatigue
  19. fainting
  20. fever
  21. itching of the skin
  22. joint or muscle pain
  23. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  24. numbness and tingling of the face, fingers, or toes
  25. pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
  26. painful or difficult urination
  27. pale, bluish-colored, or cold hands or feet
  28. pinpoint red or purple spots on the skin
  29. red, irritated eyes
  30. redness of the face, neck, arms, and occasionally, upper chest
  31. redness, soreness or itching skin
  32. shakiness in the legs, arms, hands, or feet
  33. slow or irregular heartbeat
  34. sore throat
  35. sores, ulcers, or white spots on the lips or in the mouth
  36. sores, welting, or blisters
  37. sudden sweating
  38. sweating
  39. swelling of the face, fingers, feet, or lower legs
  40. swollen glands
  41. trembling or shaking of the hands or feet
  42. unsteadiness or awkwardness
  43. unusual bleeding or bruising
  44. unusual tiredness or weakness
  45. weak or absent pulses in the legs
  46. weakness in the arms, hands, legs, or feet
  47. weight gain
  48. yellow eyes or skin

Incidence not known

  1. Abdominal or stomach pain
  2. clay-colored stools
  3. diarrhea
  4. headache
  5. loss of appetite
  6. nausea
  7. rash
  8. unpleasant breath odor
  9. vomiting of blood
  10. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Acid or sour stomach
  2. belching
  3. heartburn
  4. indigestion
  5. lack or loss of strength
  6. muscle cramps
  7. sleepiness or unusual drowsiness
  8. stomach discomfort, upset, or pain


  1. Abnormal dreams
  2. anxiety
  3. back pain
  4. bad unusual or unpleasant (after) taste
  5. bleeding gums
  6. blistering, crusting, irritation, itching, or reddening of the skin
  7. bloating
  8. bloody nose
  9. burning feeling in the chest or stomach
  10. burning while urinating
  11. burning, dry, or itching eyes
  12. change in color of the treated skin
  13. change in sense of smell
  14. change in taste
  15. changes in vision
  16. constipation
  17. continuing ringing or buzzing or other unexplained noise in the ears
  18. cracked, dry, or scaly skin
  19. decreased sexual performance or desire
  20. depression
  21. difficulty with moving
  22. difficulty with swallowing
  23. discharge, excessive tearing
  24. double vision
  25. dry mouth
  26. dryness of the skin
  27. excess air or gas in the stomach or intestines
  28. excessive muscle tone
  29. eye pain
  30. feeling of constant movement of self or surroundings
  31. feeling of unreality
  32. feeling unusually cold
  33. flushed, dry skin
  34. fruit-like breath odor
  35. full feeling
  36. general feeling of discomfort or illness
  37. hair loss or thinning of the hair
  38. headache, severe and throbbing
  39. hearing loss
  40. hyperventilation
  41. increased appetite
  42. increased hunger
  43. increased sweating
  44. increased thirst
  45. increased urge to urinate during the night
  46. increased urination
  47. irritability
  48. irritation in the mouth
  49. lack of feeling or emotion
  50. loose stools
  51. loss of memory
  52. muscle pains or stiffness
  53. muscle tension or tightness
  54. muscle weakness
  55. nervousness
  56. pain
  57. pains in the stomach, side, or abdomen, possibly radiating to the back
  58. passing gas
  59. problems with memory
  60. redness and swelling of the gums
  61. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  62. restlessness
  63. runny nose
  64. seeing double
  65. sensation of spinning
  66. sense of detachment from self or body
  67. shakiness and unsteady walk
  68. shivering
  69. sleeplessness
  70. sneezing
  71. stuffy nose
  72. sweating
  73. swollen joints
  74. tenderness in the stomach area
  75. thirst
  76. trouble in holding or releasing urine
  77. trouble sleeping
  78. twitching
  79. unable to sleep
  80. uncaring
  81. unexplained weight loss
  82. unsteadiness, trembling, or other problems with muscle control or coordination
  83. waking to urinate at night
  84. weight loss

Incidence not known

  1. Swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.