Soft tissue sarcoma care at Mayo Clinic

Two Mayo Clinic physicians discussing a case Doctors collaborate at Mayo Clinic

Mayo Clinic physicians collaborate to determine what will be the best treatment options for you.

Doctors at Mayo Clinic are respected for the experience in diagnosing and treating soft tissue sarcomas. Each year, Mayo Clinic doctors care for more than 2,400 people with soft tissue sarcoma, including very rare types.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer care by U.S. News & World Report. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2023–2024 "Best Children's Hospitals" rankings.

Your Mayo Clinic care team

At Mayo Clinic, a multidisciplinary team works together to care for people with soft tissue sarcoma. This team may include specialists in:

  • Orthopedic, general and plastic surgery.
  • Medical, surgical and radiation oncology.
  • Physical and occupational rehabilitation.
  • Psychology, social work and nutrition.
  • Other specialties as needed, such as urology, pediatric urology and others.

Advanced diagnosis and treatment

Certain subtypes of soft tissue sarcoma are susceptible to targeted therapies, so a precise diagnosis is crucial for determining exactly the right treatment for you. Mayo Clinic pathologists have the necessary expertise in diagnosing these rare types of cancer. This expertise may not be available in many other medical centers.

The range of treatments offered to people with soft tissue sarcoma includes several types of surgery. These types include minimally invasive surgery and limb-sparing surgery. The latest radiation therapy techniques also are offered, including intensity-modulated radiation therapy (IMRT), brachytherapy, proton therapy and intraoperative radiation therapy (IORT). Chemotherapy and targeted therapy also are available.

Expertise and rankings

A Mayo Clinic surgeon explains treatment options to a patient. Physician collaboration

A Mayo Clinic surgeon explains treatment options to a patient.

Mayo Clinic Comprehensive Cancer Center meets the strict standards for a National Cancer Institute comprehensive cancer center. These standards recognize scientific excellence and a multidisciplinary approach to cancer prevention, diagnosis and treatment.

All three of Mayo Clinic's campuses — in Arizona, Florida and Minnesota — have been recognized as sarcoma centers by the Sarcoma Alliance. The alliance provides education and support to people who have been diagnosed with sarcoma. Mayo Clinic researchers often participate in clinical trials sponsored by the Sarcoma Alliance for Research through Collaboration.

Mayo Clinic has been recognized as a top cancer hospital by U.S. News & World Report since it began publishing rankings in 1990. Most recently, Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, have been recognized among the top Cancer hospitals in the nation for 2023-2024 by U.S. News & World Report.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

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Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

April 27, 2023

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