Can flaxseed reduce the risk of prostate cancer?
There is limited evidence to support the idea that taking flaxseed might lower your risk of prostate cancer.
Some studies have suggested that flaxseed may have positive effects on the prostate. For instance, one study involving men diagnosed with prostate cancer found that those who took a flaxseed supplement and followed a low-fat diet saw their prostate-specific antigen (PSA) levels decline. PSA can be a measure of how fast prostate cancer is spreading.
Other studies have shown no positive effect of flaxseed — and the alpha-linolenic acid contained in flaxseed — on prostate health.
Overall, it remains unclear whether flaxseed or flaxseed oil has a role in the prevention or treatment of prostate cancer. Controlled clinical trials may help determine whether or not it's useful in the long term.
Nov. 27, 2019
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- Demark-Wahnefried W, et al. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. Cancer Epidemiology, Biomarkers and Prevention. 2008;12:3577.
- Flaxseed. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed June 20, 2017.
- Simons R. Efficacy and safety of a flaxseed hull extract in the symptomatic management of benign prostatic hyperplasia: A parallel, randomized, double-blind, placebo-controlled, pilot study. Journal of Medicinal Food. 2015;18:233.
- Leitzmann MF, et al. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. American Journal of Clinical Nutrition. 2004;80:204.
- Giovannucci E, et al. Risk factors for prostate cancer incidence and progression in the health professionals follow-up study. International Journal of Cancer. 2007;121:1571.
- Heymach JV, et al. Effect of low-fat diets on plasma levels of NF-(kappa)B-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer. Cancer Prevention Research. 2011;4:1590.
- Demark-Wahnefried W, et al. Pilot study to explore effects of low-fat, flaxseed supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen. Urology. 2004;63:900.