Print Departments and specialties Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. Departments that treat this condition Cancer Care at Mayo Clinic Men's Health Nuclear Medicine Therapy Oncology (Medical) Radiation Oncology Radiology Urology Areas that research this condition Radiology Research Urology Research Doctors who treat this condition Edit search filters close Narrow your search By location Rochester, MN By last name Find a doctor whose last name begins with the letter A A There are no doctors whose last name begins with the letter B B There are no doctors whose last name begins with the letter C C There are no doctors whose last name begins with the letter D D There are no doctors whose last name begins with the letter E E There are no doctors whose last name begins with the letter F F There are no doctors whose last name begins with the letter G G Find a doctor whose last name begins with the letter H H There are no doctors whose last name begins with the letter I I There are no doctors whose last name begins with the letter J J active Find a doctor whose last name begins with the letter K K There are no doctors whose last name begins with the letter L L There are no doctors whose last name begins with the letter M M There are no doctors whose last name begins with the letter N N There are no doctors whose last name begins with the letter O O Find a doctor whose last name begins with the letter P P There are no doctors whose last name begins with the letter Q Q There are no doctors whose last name begins with the letter R R There are no doctors whose last name begins with the letter S S There are no doctors whose last name begins with the letter T T There are no doctors whose last name begins with the letter U U There are no doctors whose last name begins with the letter V V There are no doctors whose last name begins with the letter W W There are no doctors whose last name begins with the letter X X There are no doctors whose last name begins with the letter Y Y There are no doctors whose last name begins with the letter Z Z Reset all filters Search Tips Use quotes for phrases. Even if there are no auto-suggestions within the search field, hit "Search" anyway, as you may still get results. Displaying 1-2 out of 2 doctors available Last Name Initial: K R. Jeffrey Karnes, M.D. Urologist Rochester, MN Areas of focus: Bladder removal, Prostatectomy, Urinary diversion, Open prostatectomy, Lymphadenectomy, Pelvic surgery, PSMA therapy, P...rostate cancer, Bladder cancer, Penile cancer, Metastatic prostate cancer, Recurrent cancer, Prostate cancer recurrence, Pelvic sarcoma, Metastatic castration-resistant prostate cancer, Urethral cancer Show more areas of focus for R. Jeffrey Karnes, M.D. Eugene D. Kwon, M.D. Rochester, MN Areas of focus: PSMA therapy, Prostate cancer, Metastatic prostate cancer, Metastatic castration-resistant prostate cancer ResearchMayo Clinic doctors and scientists are leaders in prostate cancer research. Areas of focus include discovering new treatment options and strategies for metastatic castration-resistant prostate cancer (mCRPC). Researchers are translating these new discoveries in order to bring them to people in the clinic sooner. Researchers also are studying new diagnostic tests and ways to enhance the quality of life for those living with advanced prostate cancer. Prostate cancer research is conducted in coordination with Mayo Clinic Comprehensive Cancer Center. Mayo Clinic Comprehensive Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center. This designation recognizes the institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment. Mayo Clinic Comprehensive Cancer Center is the only National Cancer Institute-designated comprehensive cancer center with three locations in Arizona, Florida and Minnesota. PublicationsSee a list of publications about castration-resistant prostate cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. Research Profiles Edit search filters close Narrow your search By location Arizona Florida Minnesota View all View all physicians • All Locations Andrews, Jack R. M.D. Arizona Cheville, John C. M.D. Minnesota Costello, Brian A. M.D. Minnesota Heath, Elisabeth I. M.D. Minnesota Johnson, Geoffrey B. M.D., Ph.D. Minnesota Karnes, R. Jeffrey M.D. Minnesota Kendi, Ayse Tuba M.D. Minnesota Kwon, Eugene D. M.D. Minnesota Okuno, Scott H. M.D. Minnesota Orme, Jacob J. M.D., Ph.D. Minnesota Pagliaro, Lance C. M.D. Minnesota Riaz, Irbaz B. M.B.B.S., Ph.D. Arizona Singh, Parminder M.D. Arizona Tan, Winston M.D. Florida Thorpe, Matt P. M.D., Ph.D. Minnesota By Mayo Clinic Staff Metastatic castration-resistant prostate cancer (mCRPC) care at Mayo Clinic Request an appointment Survival ratesCare at Mayo Clinic Dec. 24, 2025 Print Related Associated Procedures Biological therapy for cancer Bone scan Cancer treatment Chemotherapy Choline C-11 PET scan CT scan Genetic testing Hormone therapy for prostate cancer MRI Palliative care Positron emission tomography scan PSA test PSMA PET scan for prostate cancer Radiation therapy Radiopharmaceuticals Stereotactic body radiotherapy Show more associated procedures Metastatic castration-resistant prostate cancer (mCRPC)Symptoms&causesDiagnosis&treatmentSurvivalratesDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20590535 Diseases & Conditions Metastatic castration-resistant prostate cancer (mCRPC)