Below are current clinical trials.15 studies in Dementia
(open studies only).
Filter this list of studies by location, status and more.
The purpose of this study is ongoing longitudinal clinicopathologic studies of normal aging and Parkinson's Disease subjects. Specific projects of motor, non-motor and peripheral manifestations of Parkinson’s disease (PD) as possible early markers of PD onset in otherwise asymptomatic elderly people. Cognitive and non-cognitive markers of eventual dementia onset in previously non-demented persons with PD.
This study is being done to learn more about possible ways in which the brain might stop working properly before the first signs of Alzheimer’s disease. In addition, it is hoped that the methods used to study and identify brain abnormalities before memory loss begins, will help to identify people who might benefit most from preventive therapy. It is also hoped that it will create a faster way to study new preventative treatments when they become available to test.
This study is being done to learn more about normal memory and aging, mild memory and thinking problems, Alzheimer's disease and other forms of dementia. This study will help us determine how often memory problems occur in people in our community, and help to identify factors that may influence changes in memory and thinking skills.
The purpose of this study is to learn more about Lewy Body disease and a skin condition called Bullous Pemphigoid.
The goal of this study is to gain a better understanding of the status of advanced care planning among caregivers of patients with dementia and examine how this differs by race and disease stage.
Jacksonville, Fla., Rochester, Minn.
This study is being done to learn more about normal thinking and behavior, mild thinking and behavior problems, Frontotemporal Dementia and other forms of dementia in families in which one or more relatives have a mutation associated with Frontotemporal Dementia.
The goal of this study is to establish and maintain a neurology disease biospecimen bank containing samples of blood and/or cerebral spinal fluid from patients with symptoms of cognitive decline as well as patients with symptoms of Parkinson’s disease.
The main objective of this research project is to provide a comprehensive clinical database of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to identify cognitively normal individuals at genetically defined risk for Alzheimer's disease through genetic screening.
All participants are seen annually. Autopsies to establish diagnoses in patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.
The purpose of this study is to use a specific gene panel to assist in the diagnosis of a hereditary form of young onset dementia.
Scottsdale/Phoenix, Ariz., Rochester, Minn.
The purpose of this study is to establish a repository consisting of clinical information, radiological data, serum, peripheral blood lymphocytes, plasma, cerebrospinal fluid (CSF), urine, stool, DNA and tissue specimens collected from patients who have central nervous system (CNS) inflammatory diseases.
April 05, 2016
- What is dementia? Alzheimer's Association. http://www.alz.org/what-is-dementia.asp. Accessed Feb. 12, 2016.
- Dementia: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dementias/detail_dementia.htm?css. Accessed Feb. 12, 2016.
- Larson EB. Evaluation of cognitive impairment of dementia. http://www.uptodate.com/home. Accessed Feb. 12, 2016.
- Dementia. Merck Manual Professional Version. http://www.merckmanuals.com/professional/neurologic-disorders/delirium-and-dementia/dementia. Accessed Feb. 12, 2016.
- AAN guideline summary for clinicians: Detection, diagnosis and management of dementia. American Academy of Neurology. https://www.aan.com/Guidelines/Home/ByTopic?topicId=15. Accessed Feb. 15, 2016.
- Press D, et al. Treatment of dementia. http://www.uptodate.com/home. Accessed Feb. 12, 2016.
- Caring for a person with Alzheimer's disease. National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/caring-person-alzheimers-disease/about-guide. Accessed Feb. 12, 2016.
- Preventing Alzheimer's disease: What do we know? National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/preventing-alzheimers-disease/introduction. Accessed Feb. 12, 2016.
- Natural medicines in the clinical management of Alzheimer's disease. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Feb. 15, 2016.
- Press D, et al. Prevention of dementia. http://www.uptodate.com/home. Accessed Feb. 15, 2016.
- Graff-Radford, NR (expert opinion). Mayo Clinic, Jacksonville, Fla. Feb. 26, 2016.