Chondrosarcoma

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Stages

Stage describes how far a cancer has spread.

Bone sarcomas can be staged using systems that consider tumor grade, and whether the cancer has extended beyond its original area, such as to your lungs. The staging system depends on where the bone cancer starts. For example, cancers in the arms, legs, trunk, skull or facial bones are staged differently from cancers in the pelvis or spine.

Staging tests

Tests used for staging assess a tumor's location and grade. Healthcare professionals look at how far higher grade chondrosarcomas have spread and whether these cancers have gone to the lungs. Your care team may check your lungs because aggressive chondrosarcomas often spread there.

Imaging of the primary tumor also helps determine its size and extent. These findings, together with the grade and information about distant spread, help your care team plan treatment.

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Diagnosis & treatmentDoctors & departments
Sept. 23, 2026

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Sarcoma Discussions

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  2. Gelderblom AJ, et al. Chondrosarcoma. https://www.uptodate.com/contents/search. Accessed Sept. 3, 2026.
  3. Jeys LM, et al. Identifying consensus and areas for future research in chondrosarcoma: A report from the Birmingham Orthopaedic Oncology Meeting. The Bone & Joint Journal. 2025; doi:10.1302/0301-620X.107B2.BJJ-2024-0643.R1.
  4. Gerrand C, et al. UK guidelines for the management of bone sarcomas. British Journal of Cancer. 2025; doi:10.1038/s41416-024-02868-4.
  5. Winn HR, ed. Chordomas and chondrosarcomas. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed Sept. 3, 2026.
  6. Michaeli O, et al. Update on cancer screening in children with syndromes of bone lesions, hereditary leiomyomatosis and renal cell carcinoma syndrome, and other rare syndromes. Clinical Cancer Research. 2025; doi:10.1158/1078-0432.CCR-24-2171.
  7. Sambri A, et al. Grade 2 central chondrosarcoma treated by intralesional curettage: Observation or surgery? The Bone & Joint Journal. 2025; doi:10.1302/0301-620X.107B9.BJJ-2024-1378.R1.
  8. Remiszewski P, et al. Chemotherapy in dedifferentiated chondrosarcoma: From neoadjuvant to palliative treatment options. Critical Reviews in Oncology/Hematology. 2026; doi:10.1016/j.critrevonc.2026.105297.
  9. Tsukamoto S, et al. A systematic review of adjuvant chemotherapy in localized dedifferentiated chondrosarcoma. Current Oncology. 2024; doi:10.3390/curroncol31010040.
  10. Yu A, et al. The impact of chondrosarcoma with positive margins and extraosseous extension on patient outcomes. Journal of Surgical Oncology. 2025; doi:10.1002/jso.27982.
  11. Sullivan MH, et al. Chondrosarcoma of the flat bones: differential survival between high-grade lesions of the pelvis and scapula. Journal of Surgical Oncology. 2025; doi:10.1002/jso.28023.
  12. Ioakeim-Ioannidou M, et al. Prospective, randomized dose-escalation trial with proton-based radiation for skull base and cervical spine chondrosarcomas: 30-year outcomes from PROG 85-26. Neuro-Oncology. 2026; doi:10.1093/neuonc/noaf289.
  13. Han R, et al. Effectiveness of question prompt list interventions for patients with cancer: A systematic review and meta-analysis of randomized controlled trials. Asia-Pacific Journal of Oncology Nursing. 2025; doi:10.1016/j.apjon.2025.100765.
  14. Bone cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1418NCCN. Accessed Sept. 18, 2026.

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