Overview

It can be scary to see blood in urine, also called hematuria. In many cases, the cause is harmless. But blood in urine also can be a sign of a serious illness.

If you can see the blood, it's called gross hematuria. Blood that can't be seen with the naked eye is called microscopic hematuria. It's such a small amount that it can be seen only under a microscope when a lab tests the urine. Either way, it's important to figure out the reason for the bleeding.

Treatment depends on the cause.

Symptoms

Blood in the urine can look pink, red or cola-colored. Red blood cells cause the urine to change color. It takes only a small amount of blood to turn urine red.

The bleeding often isn't painful. But if blood clots get passed in the urine, that can hurt.

When to see a doctor

See a health care provider whenever urine looks like it might have blood in it.

Red urine isn't always caused by red blood cells. Some medicines can cause urine to turn red, such as a medicine called phenazopyridine that eases urinary tract symptoms. Certain foods also can turn urine red, including beets and rhubarb.

It can be hard to tell whether a change of urine color is caused by blood. That's why it's always best to get a checkup.

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Causes

This condition happens when the kidneys or other parts of the urinary tract let blood cells leak into urine. Different problems can cause this leaking to happen, including:

  • Urinary tract infections (UTIs). These happen when bacteria get into the tube through which urine leaves the body, called the urethra. Then the bacteria multiply in the bladder. UTIs can cause bleeding that makes urine look red, pink or brown. With a UTI, you also may have a strong urge to pee that lasts a long time. You may have pain and burning while peeing. Your urine may have a very strong smell too.
  • Kidney infection. This type of UTI also is called pyelonephritis. Kidney infections can happen when bacteria enter the kidneys from the bloodstream. Infections also can happen when bacteria move to the kidneys from a pair of tubes that connect the kidneys with the bladder, called the ureters. Kidney infections can cause the same urine-related symptoms that other UTIs can. But they're more likely to cause a fever and pain in the back, side or groin.
  • A bladder or kidney stone. The minerals in urine can form crystals on the walls of the kidneys or bladder. Over time, the crystals can become small, hard stones.

    The stones are often painless. But they can hurt a lot if they cause a blockage or leave the body through urine. Bladder or kidney stones can cause blood in urine that can be seen with the naked eye as well as bleeding that can be seen only in the lab.

  • Enlarged prostate. The prostate gland is just below the bladder, and it surrounds the top part of the urethra. It often gets bigger toward middle age. It then puts pressure on the urethra, partly blocking the flow of urine. With an enlarged prostate, you might have trouble peeing, an urgent or lasting need to pee, or blood in the urine. Infection of the prostate, called prostatitis, can cause the same symptoms.
  • Kidney disease. Blood in urine that can be seen only in the lab is a common symptom of a kidney disease called glomerulonephritis. With this disease, the tiny filters in the kidneys that remove waste from blood become inflamed.

    Glomerulonephritis may be part of a condition that affects the whole body, such as diabetes. Or it can happen on its own.

  • Cancer. Blood in urine that can be seen with the naked eye may be a sign of advanced kidney, bladder or prostate cancer. These cancers might not cause symptoms sooner, when treatments could work better.
  • Inherited illnesses. A genetic condition that affects red blood cells, called sickle cell anemia, can cause blood in urine. The blood cells could be visible or too tiny to see. A condition that damages tiny blood vessels in the kidneys, called Alport syndrome, also can cause blood in the urine.
  • Kidney injury. A blow or other injury to the kidneys from an accident or contact sports can cause blood to show up in urine.
  • Medicines. The anti-cancer drug cyclophosphamide (Cytoxan) and the antibiotic penicillin are linked to blood in urine. Medicines that prevent blood clots also are tied to blood in urine. These include medicines that keep blood cells called platelets from sticking together, such as the pain reliever aspirin. Medicines that thin the blood, such as heparin, also may be a cause.
  • Hard exercise. Blood in the urine can happen after playing contact sports, such as football. It may be linked to bladder damage caused by getting hit. Blood in urine also can happen with long-distance sports, such as marathon running, but it's less clear why. It may be linked to bladder damage or other reasons that don't involve an injury. When hard exercise causes blood in urine, it may go away on its own within a week.

    If you see blood in your urine after exercise, don't assume it's from exercising. See your health care provider.

Often the cause of hematuria is unknown.

Risk factors

Almost anyone can have red blood cells in the urine. This includes children and teens. Some things that can raise the risk of blood in the urine include:

  • Age. Middle-aged and older men may be more likely to have hematuria due to an enlarged prostate gland. The risk of some cancers that can cause blood in urine also may rise after the age of 50.
  • Urinary tract infection. This is one of the top causes of blood that can be seen in children's urine.
  • Family history. The chances of having blood in the urine may go up if one or more family members have had kidney disease.
  • Certain medicines. Some pain relievers, blood thinners and antibiotics can raise the risk of blood in urine.
  • Hard exercise. Marathon runner's hematuria is one nickname for hematuria. Contact sports can raise the risk too.

Jan. 07, 2023

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  1. Perzella M, et al. Etiology and evaluation of hematuria in adults. https://www.uptodate.com/contents/search. Accessed Nov. 4, 2022.
  2. Blood in urine (hematuria): Causes and treatment. American Kidney Fund. https://www.kidneyfund.org/all-about-kidneys/other-kidney-problems/blood-urine-hematuria. Accessed Nov. 7, 2022.
  3. Hematuria in adults. National Kidney Foundation. https://www.kidney.org/atoz/content/hematuria-adults. Accessed Nov. 4, 2022.
  4. Isolated hematuria. Merck Manual Professional Version. https://www.merckmanuals.com/professional/genitourinary-disorders/symptoms-of-genitourinary-disorders/isolated-hematuria. Accessed Nov. 4, 2022.
  5. Medical student curriculum: Hematuria. American Urological Association. https://www.auanet.org/meetings-and-education/for-medical-students/medical-students-curriculum/hematuria. Accessed Nov. 4, 2022.
  6. Mercieri A. Exercise-induced hematuria. https://www.uptodate.com/contents/search. Accessed Nov. 4, 2022.
  7. Wein AJ, et al., eds. Evaluation of the urologic patient: History and physical examination. In: Campbell-Walsh-Wein Urology. 12th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Nov. 4, 2022.
  8. Urinary tract infection. Centers for Disease Control and Prevention. https://www.cdc.gov/antibiotic-use/uti.html. Accessed Nov. 17, 2022.
  9. Wein AJ, et al., eds. Benign prostatic hyperplasia: Etiology, pathophysiology, epidemiology, and natural history. In: Campbell-Walsh-Wein Urology. 12th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Nov. 29, 2022.
  10. Boyer O. Evaluation of gross hematuria in children. https://www.uptodate.com/contents/search. Accessed Nov. 8, 2022.
  11. Bladder cancer risk factors. American Cancer Society. https://www.cancer.org/cancer/bladder-cancer/causes-risks-prevention/risk-factors.html. Accessed Nov. 17, 2022.
  12. Ferri FF. H — Differential diagnosis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed Nov. 8, 2022.
  13. Cheng L, et al., eds. Urine cytology. In: Urologic Surgical Pathology. 4th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Dec. 8, 2022.

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