Tests and procedures used to diagnose adrenal cancer include:
- Blood and urine tests. Laboratory tests of your blood and urine may reveal unusual levels of hormones produced by the adrenal glands, including cortisol, aldosterone and androgens.
- Imaging tests. Your doctor may recommend CT, MRI or positron emission tomography (PET) scans to better understand any growths on your adrenal glands and to see if cancer has spread to other areas of your body, such as your lungs or your liver.
- Laboratory analysis of your adrenal gland. If your doctor suspects you may have adrenal cancer, he or she may recommend removing the affected adrenal gland. The gland is analyzed in a laboratory by a doctor who studies body tissues (pathologist). This analysis can confirm whether you have cancer and exactly what types of cells are involved.
Adrenal cancer treatment usually involves surgery to remove all of the cancer. Other treatments might be used to prevent the cancer from coming back or if surgery isn't an option.
The goal of surgery is to remove the entire adrenal cancer. To achieve this, doctors must remove the all of the affected adrenal gland (adrenalectomy).
If surgeons find evidence that cancer has spread to nearby structures, such as the liver or kidney, parts or all of those organs might also be removed during the operation.
Medication to reduce the risk of recurrence
An older drug that has been used to treat advanced adrenal cancer has shown promise in delaying the recurrence of the disease after surgery. Mitotane (Lysodren) may be recommended after surgery for people with a high risk of cancer recurrence. Research into mitotane for this use is ongoing.
Radiation therapy uses high-powered beams of energy, such as X-rays and protons, to kill cancer cells. Radiation therapy is sometimes used after adrenal cancer surgery to kill any cells that might remain. It can also help reduce pain and other symptoms of cancer that has spread to other parts of the body, such as the bone.
Chemotherapy is a drug treatment that uses chemicals to kill cancer cells. For adrenal cancers that can't be removed with surgery or that return after initial treatments, chemotherapy may be an option to slow the progression of the cancer.
Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
Coping and support
With time, you'll find what helps you cope with the uncertainty and distress that comes with a cancer diagnosis. Until then, you may find it helps to:
- Learn enough about adrenal cancer to make decisions about your care. Ask your doctor about your cancer, including your test results, treatment options and, if you like, your prognosis. As you learn more about cancer, you may become more confident in making treatment decisions.
- Keep friends and family close. Keeping your close relationships strong will help you deal with your cancer. Friends and family can provide the practical support you'll need, such as helping take care of your house if you're in the hospital. And they can serve as emotional support when you feel overwhelmed by cancer.
Find someone to talk with. Find a good listener who is willing to listen to you talk about your hopes and fears. This may be a friend or family member. The concern and understanding of a counselor, medical social worker, clergy member or cancer support group also may be helpful.
Ask your doctor about support groups in your area. Other sources of information include the National Cancer Institute and the American Cancer Society.
Preparing for your appointment
Start by making an appointment with your doctor if you have any signs or symptoms that worry you.
Here's some information to help you get ready for your appointment.
What you can do
When you make the appointment, ask if there's anything you need to do in advance, such as fasting before having a specific test. Make a list of:
- Your symptoms, including any that seem unrelated to the reason for your appointment
- Key personal information, including major stresses, recent life changes and family medical history
- All medications, vitamins or other supplements you take, including the doses
- Questions to ask your doctor
Bring a family member or friend with you, if possible, to help remember the information you're given.
For adrenal cancer, some basic questions to ask your doctor include:
- What's likely causing my symptoms?
- Other than the most likely cause, what are other possible causes for my symptoms?
- What tests do I need?
- What's the best course of action?
- What are the alternatives to the primary approach you're suggesting?
- I have these other health conditions. How can I best manage them together?
- Are there restrictions I need to follow?
- Should I see a specialist?
- Are there brochures or other printed material I can have? What websites do you recommend?
Don't hesitate to ask other questions.
What to expect from your doctor
Your doctor is likely to ask you several questions, such as:
- When did your symptoms begin?
- Have your symptoms been continuous or occasional?
- How severe are your symptoms?
- What, if anything, seems to improve your symptoms?
- What, if anything, appears to worsen your symptoms?
Nov. 24, 2020