Clinical trials Below are current clinical trials.128 studies in Surgery (open studies only). Filter this list of studies by location, status and more. A Study to Evaluate Biomarker Target Stimulation Rochester, Minn. The purpose of this study is to understand how electrical stimulation of the brain can modulate and suppress interictal epileptiform activity as a step on the path to developing new therapies for epilepsy. A Study Of Acute Stimulation For The Modulation Of Epileptic Events With A Closed-Loop Brain Interchange System In Drug Resistant Epilepsy Rochester, Minn. The purpose of this study is to investigate the feasibility of detecting and modulating pathological high-frequency oscillations (HFOs) generated by the seizure onset zone (SOZ) of drug-resistant epilepsy patients using CorTec's Brain Interchange Evaluation Kit (manual provided as supplementary material). Feasibility Of Intraoperative Microdialysis During Neurosurgery For Central Nervous System Malignancies Rochester, Minn. This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intraoperative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors to develop new strategies to better diagnose, monitor, and treat brain tumors. CTSN Embolic Protection Trial Rochester, Minn. The purpose of this study is to analyze the effectiveness and safety of an embolic protection device compared to a standard aortic cannula to reduce the effects of death, clinical stroke, delirium and acute kidney injury in high-risk valve surgery patients. A Study to Evaluate a Virtual Assistant for Plastic Surgery Patients Jacksonville, Fla. The purpose of this study is to determine the impact of a recently developed artificial intelligence virtual assistant (AIVA) on plastic surgery patients and providers’ experience and leverage the use of new technologies to promote high-quality service and meaningful relationships between plastic surgeons and patients. A Study to Evaluate Perceptions of Midline Sternotomy Scar in Children and Young Adults Rochester, Minn. The purpose of this study is to evaluate how children and young adults perceive their midline sternotomy scars (in terms of appearance, associated symptoms, consciousness, satisfaction with appearance/symptoms, and impact on quality of life)? Brachial plexus patients undergoing upper limb amputation Rochester, Minn. The purpose of this study is to follow Mayo Clinic patients with severe brachial plexus injuries who underwent upper limb amputation. Digital Biomarker And Omics-Based Assessment Of Surgical Resiliency In Children Undergoing Solid Tumor Resection Rochester, Minn. The purpose of this study is to demonstrate 1) feasibility of digital biomarker assessment using wearable in children with solid tumors who undergo surgery and 2) alterations in circulating proteins and metabolites indicative of a stressed state will persist postoperatively and correlate with clinical signs of recovery. A Study to Evaluate Time to First Movement for Fetal Surgery Patients Injected with Intramuscular Anesthesia Rochester, Minn. The purpose of this study is to determine the time from intramuscular injection to the time of first fetal movement after a fetal surgery procedure. A Study to Evaluate Long-term Outcomes of Pollicization Rochester, Minn. The purpose of this study is to assess long-term functional outcomes after pollicization. Pagination Clinical studies PrevPrevious Page Go to page 55 Go to page 66 Go to page 77 Go to page 88 Go to page 99 NextNext Page Request an appointment Expertise & rankingsResearch April 04, 2026 Share on: FacebookTwitter SurgerySectionsOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferralsFrozen SectionPathology Lab Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an AppointmentOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20475391 Medical Departments & Centers Surgery