Clinical trials Below are current clinical trials.131 studies in Surgery (open studies only). Filter this list of studies by location, status and more. Treatment Resistant Depression Subcallosal Cingulate Network Rochester, Minn. The purpose of this study is to evaluate the effectiveness and safety of bilateral stimulation of the SCCwm using the Infinity DBS system as an adjunctive treatment of non-psychotic unipolar Major Depression Disorder (MDD) for adults who are experiencing an Major Depressive Episode (MDE) with inadequate response to 4 or more antidepressant treatments. A Study to Evaluate Outcomes of Shoulder Arthroplasty Rochester, Minn. The purpose of this study is to evaluate the outcomes and complications in patients who have received a hemiarthroplasty, anatomic total shoulder, or reverse total shoulder arthroplasty. A Study to Compare the Cosmetic Outcome of Superomedial and Inferior Pedicle Breast Reduction Rochester, Minn. The purpose of this study is to compare the cosmetic outcome of Superomedial and Inferior Pedical Breast Reduction. A Study To Analyze Surgical Outcomes And Predictors Of Treatment For Hip Diseases Rochester, Minn. This study is designed to: -analyze effects of surgical treatment -improve surgical care and quality of life of patients with hip problems/diseases -ID predictors of surgical outcomes to identify/improve future treatments -Collect data, images, from patients undergoing surgical treatment of hip disorders (we will not be collecting social security numbers to send to Washington University). A Study To Evaluate Mesenchymal Stem Cells For Reducing Anastomotic Stenosis Jacksonville, Fla. The purpose of this study is evaluate the safety of allogeneic adipose derived mesenchymal stem cell (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its effectiveness on improving access maturation and primary anastomotic patency. Patient-Centered Outcomes In The Surgical Treatment Of Uterovaginal Prolapse Jacksonville, Fla., Rochester, Minn. The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications. STAR Trial (Siegel Transcatheter Aortic Valve Replacement In Patients With Symptomatic Severe Aortic Stenosis) Jacksonville, Fla., Rochester, Minn. To evaluate the safety and efficacy of Siegel™ TAVR System in the treatment of subjects with symptomatic severe native aortic stenosis. BoxX-NoAF Clinical Trial Rochester, Minn. Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial to evaluate if prophylactic ablation and exclusion of the Left Atrial Appendage at the time of other routine cardiac surgery can reduce the incidence of post operative AF and clinical AF during long term follow up in patients who have not yet developed AF but are at risk. A Study to Establish a Pediatric Spine Registry Rochester, Minn., Minneapolis, Minn. The purpose of this study is to collect data about patients with chest wall and spinal deformities to develop a multicenter registry. This will speed the pace of medical advancement and treatment recommendations for these conditions. A Study to Analyze Intracerebral Hemorrhage Hematoma Jacksonville, Fla. The purpose of this study is to to take the usual waste material from the removal of hematoma and apply an array of -Omics approaches (including for example genomics, transcriptomics, lipidomics, proteomics, and metabolomics) to identify biomarkers that assess prognosis and identify key therapeutic targets. Pagination Clinical studies PrevPrevious Page Go to page 88 Go to page 99 Go to page 1010 Go to page 1111 Go to page 1212 NextNext Page Request an appointment Expertise & rankingsResearch April 04, 2026 Share on: FacebookTwitter SurgerySectionsOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferralsFrozen SectionPathology Lab Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an AppointmentOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20475391 Medical Departments & Centers Surgery