Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study To Analyze Surgical Outcomes And Predictors Of Treatment For Hip Diseases

   Rochester, Minn.

   This study is designed to:
   -analyze effects of surgical treatment
   -improve surgical care and quality of life of patients with hip problems/diseases
   -ID predictors of surgical outcomes to identify/improve future treatments
   -Collect data, images, from patients undergoing surgical treatment of hip disorders (we will not be collecting social security numbers to send to Washington University).

2. A Study To Evaluate Mesenchymal Stem Cells For Reducing Anastomotic Stenosis

   Jacksonville, Fla.

   The purpose of this study is evaluate the safety of allogeneic adipose derived mesenchymal stem cell (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its effectiveness on improving access maturation and primary anastomotic patency.

3. Patient-Centered Outcomes In The Surgical Treatment Of Uterovaginal Prolapse

   Jacksonville, Fla., Rochester, Minn.

   The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.

4. BoxX-NoAF Clinical Trial

   Rochester, Minn.

   Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial to evaluate if prophylactic ablation and exclusion of the Left Atrial Appendage at the time of other routine cardiac surgery can reduce the incidence of post operative AF and clinical AF during long term follow up in patients who have not yet developed AF but are at risk.

5. STAR Trial (Siegel Transcatheter Aortic Valve Replacement In Patients With Symptomatic Severe Aortic Stenosis)

   Jacksonville, Fla., Rochester, Minn.

   To evaluate the safety and efficacy of Siegel™ TAVR System in the treatment of subjects with symptomatic severe native aortic stenosis.

6. A Study to Establish a Pediatric Spine Registry

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to collect data about patients with chest wall and spinal deformities to develop a multicenter registry.  This will speed the pace of medical advancement and treatment recommendations for these conditions. 

7. A Study to Analyze Intracerebral Hemorrhage Hematoma

   Jacksonville, Fla.

   The purpose of this study is to to take the usual waste material from the removal of hematoma and apply an array of -Omics approaches (including for example genomics, transcriptomics, lipidomics, proteomics, and metabolomics) to identify biomarkers that assess prognosis and identify key therapeutic targets.

8. Leveraging AI/ML Algorithms On Digital Pathology And Ex-Vivo Confocal Microscopy Imaging For Extramammary Paget’s Disease

   Rochester, Minn.

   The purpose of this study is to validate the use of ex-vivo confocal microscopy for the assessment of skin specimens derived from Mohs surgery compared to standard microscopy. To leverage deep learning models for classification, detection, and localization of tumor for extramammary Paget’s disease on ex-vivo confocal microscopy images. To leverage AI/ML to ex-vivo confocal microscopy imaging to facilitate microscopic-level imaging of extramammary Paget’s disease. To leverage deep learning models for classification, detection, and localization of tumor for extramammary Paget’s disease on frozen and permanent pathology WSIs.

9. CT Angiography of the Aorta following Fenestrated Branched Endovascular Aneurysm Repair (F-BEVAR) using Tube Potential Selection and Weight-based Method: Effects on Image Quality and Radiation Dose

   Rochester, Minn.

   The objective of this study is to evaluate the image quality and radiation dose of a CT angiography protocol (CTA) using tube potential selection and weight-based method.

10. Pituitary tumor registry

    Rochester, Minn.

    The purpose of this data registry involves the collection of standard of care clinical treatment regimens, diagnostic information and surgical outcomes which may include human specimens and associated genomewide expression data.