Below are current clinical trials.16 studies in Kidney Transplant Program
(open studies only).
Filter this list of studies by location, status and more.
To evaluate the efficacy of Cinryze® given for the treatment of acute antibody-mediated rejection (of renal allograft) (AMR) in kidney transplant recipients as measured by the proportion of subjects with new or worsening transplant glomerulopathy (TG) at 6 months after treatment initiation.
The purpose of this study is to to determine the safety and effectivness of a single dose of autologous polyTregs or darTregs in renal transplant recipients with subclinical inflammation (SCI) in the 6 month post‐transplant allograft protocol biopsy compared to control patients treated with CNI‐based immunosuppression.
The purpose of this study is to confirm the effectiveness and safety of intravenous terlipressin in the treatment of adult patients who have hepatorenal syndrome (HRS) type 1.
The purpose of this pilot study is to investigate whether contrast-enhanced ultrasound (CEUS) may help evaluate segmental differences in renal perfusion better than doppler ultrasound and thus help direct a biopsy to the most abnormal part of the renal cortex.
The aim of this study is to determine the validity of two tests on bone marrow of sensitized kidney transplant recipients in order to better understand why these patients with antibodies against their donors are at a greater risk of rejection of their transplanted organs.
Frailty is a condition characterized by slowness, weakness, low physical activity, wasting, and exhaustion. Frailty increases the risk for adverse outcomes following transplant such as increased length of stay in the hospital, mortality, or graft function. No interventions for frailty are known for patients with renal disease, but exercise programs like pulmonary rehabilitation have been effective in improving frailty in patients with other diseases, such as lung disease. The goal of this study is to test whether exercise will also improve frailty among patients who are waiting for a kidney transplant and who are considered frail or pre-frail.
Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this double-blind, randomized-withdrawal, placebo-controlled study in kidney transplant patients with AMR is to evaluate the efficacy and safety of human plasma-derived C1-esterase inhibitor as add-on to standard of care (IVIG).
Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.
The primary objective of this study is to demonstrate the safety and efficacy of cellular immunotherapy with MDR-101 for induction of functional immune tolerance in recipients of human leukocyte antigen (HLA)-matched, living donor kidney transplants.
The aim of this study is to assess the quality of life among a sample of obese liver transplant recipients and compare it between those who underwent sleeve gastrectomy and those who did not.
Jacksonville, Fla., Rochester, Minn.
This study is being done to collect and store samples of blood from patients with liver disease for a research study to be able to find a new and better way to detect liver cancer.
Sept. 11, 2018
- Scientific Registry of Transplant Recipients. http://www.srtr.org/default.aspx. Accessed April 7, 2016.
- U.S. News & World Report. U.S. News Best Hospitals 2015-16. http://health.usnews.com/best-hospitals/rankings. Accessed Feb. 22, 2016.
- Orandi BJ, et al. Kidney transplants from incompatible live donors. New England Journal of Medicine. 2016;374:940.
- Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. April 5, 2016.
- Schinstock CA (expert opinion). Mayo Clinic, Rochester, Minn. April 18, 2014.
- Lallas CD, et al. The development of a laparoscopic donor nephrectomy program in a de novo renal transplant program: Evolution of technique and results in over 200 cases. Journal of the Society of Laparoendoscopic Surgeons. 2006;10:135.
- Mai ML (expert opinion). Mayo Clinic, Jacksonville, Fla. April 26, 2016.
- Stulak JM, et al. Combined heart and abdominal organ transplantation: Excellent outcomes gained from a unique experience. Journal of Heart and Lung Transplantation. 2014;33:S278.
- Li H, et al. Assessing the efficacy of kidney paired donation — Performance of an integrated three-site program. Transplantation. 2014;98:300.
- Cornell LD, et al. Positive crossmatch kidney transplant recipients treated with eculizumab: Outcomes beyond 1 year. American Journal of Transplantation. 2015;15:1293.
- Shapiro R, et al. Benefits and complications of laparoscopic donor nephrectomy. http://www.uptodate.com/home. Accessed March 11, 2016.
- Polycystic kidney disease. National Institutes of Diabetes and Digestive Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/polycystic/. Accessed March 16, 2016.
- Raichlin E, et al. Combined heart and kidney transplantation provides an excellent survival and decreases risk of cardiac cellular rejection and coronary allograft vasculopathy. Transplantation Proceedings. 2011;43:1871.
- Heilman RL, et al. Steroid avoidance immunosuppression in low-risk kidney transplant recipients. Transplantation Proceedings. 2005;37:1785.
- Jay CL, et al. Reassessing preemptive kidney transplantation in the United States: Are we making progress? Transplantation. 20165;100:1120. http://www.transplantjournal.com. Accessed April 6, 2016.
- Bentall A, et al. Five-year outcomes in living donor kidney transplants with a positive crossmatch. American Journal of Transplantation. 2013;13:76.
- Prieto M (expert opinion). Mayo Clinic, Rochester, Minn. May 11, 2016.
- Dharnidharka VR, et al. Kidney transplantation in children. New England Journal of Medicine. 2014;371:549.
- Barbara Woodward Lips Patient Education Center. Your child's kidney transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
- Kidney transplant team describes current work. Mayovox. 1967;18:24.
- Kudva YC (expert opinion). Mayo Clinic, Rochester, Minn. March 14, 2016.
- Barbara Woodward Lips Patient Education Center. Kidney transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
- Rossi AP, et al. Evaluation of the potential renal transplant recipient. http://www.uptodate.com/home. Accessed April 6, 2016.
- Cramer CH II (expert opinion). Mayo Clinic, Rochester, Minn. April 27, 2016.
- Li H, et al. The limits of paired donation — Who doesn't get transplanted? American Journal of Transplantation. 2013;13(suppl 5). http://www.atcmeetingsabstracts.com/abstract/limits-of-paired-donation-who-doesn’t-get-transplanted-the/. Accessed April 27, 2016.
- Crespo HS, et al. Kidney transplantation in the septuagenarian. American Journal of Transplantation. 2015;15(suppl 3). http://www.atcmeetingabstracts.com/abstract/kidney-transplantation-in-the-septuagenarian/. Accessed April 27, 2016.
- Taner T, et al. Decreased chronic cellular and antibody-mediated injury in the kidney following simultaneous liver-kidney transplantation. Kidney International. 2016:89:909.
Kidney Transplant Program