Hospital Internal Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study of Bone Microstructure and Bone Strength Using High-Resolution CT Scanning in Adults with Repeat Fractures

   Rochester, Minn.

   The purpose of this study is to obtain more detailed information about bone structure in adults with repeat bone fractures.

    

2. A Multimodal Monitoring (MMM) Computer to Detect Physiologic Trends in Data in Neurointensive Care Unit Patients

   Rochester, Minn., Jacksonville, Fla.

   The purpose of this study is to identify important physiologic trends in bedside ICU data such as cerebral perfusion pressure (CPP), intracranial pressure (ICP) using a bedside “Multimodal monitoring” (MMM) computer which utilizes ICM+ Cambridge software.

3. RLY-2608-201-Ph2 Study Of RLY-2608 In PROS And PIK3CA Driven Malformations

   Rochester, Minn.

   The purpose of this study is to compare the efficacy and safety of RLY-2608 versus placebo in adult, adolescent, and pediatric participants with PROS and malformations driven by PIK3CA mutations, which is preceded by a dose selection and basket design with exploratory single-arm cohorts for various subpopulations of participants.

4. A Study to Establish a Rochester Older Adult Registry (ROAR)

   Rochester, Minn.

   The purpose of this study is to create an older adult registry from a primary care population and to identify patients who may be eligible for participation in future research studies.

5. To Assess The Efficacy, Safety, And Tolerability Of INCB000928 In Participants With Fibrodysplasia Ossificans Progressiva

   Rochester, Minn.

   This Phase 2, Randomized, Double-Blind, Placebo-Controlled Study is intended to evaluate the Efficacy, Safety, and Tolerability and PK of INCB000928 administered to participants with a clinical diagnosis of fibrodysplasia ossificans progressiva (FOP).

6. Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery (DISCOVERY)

   Rochester, Minn.

   The purpose o fthis study

   A total of 8,000 patients presenting to CPSs with acute-onset AIS, ICH or aSAH and no history of dementia will be enrolled within 6 weeks of stroke onset.

   All participants will undergo baseline screening for evidence of pre-stroke dementia. Those who pass baseline screening will complete a blood draw and a series of cognitive and functional assessments at baseline.

   Participants will undergo in-person (3-6 months, 18 months) and telephone (annual) follow-up visits for the duration of the study to assess for longitudinal cognitive and functional outcomes. In addition to Tier 1 procedures, at each in-person follow-up visit: Tier 2 participants will also undergo MRI scanning, comprehensive cognitive assessment batteries and longitudinal blood collection; and Tier 3 participants will also complete amyloid- and tau-PET/CT scans.

7. A Study of The Impact of Predictive Modeling On Time to Palliative Care Review in an Inpatient Hospital Population

   Rochester, Minn.

   The purpose of this study is to assess the effectiveness and implementation of the Control Tower palliative care algorithm into hospital practice.