Hospital Internal Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Evaluate Voice-enabled Artificial Intelligence to Diagnosis Hepatic Encephalopathy

   Rochester, Minn.

   early detection of hepatic encephalopathy

2. A Study to Assess Neuromuscular Ultrasound to Predict the Duration of Mechanical Ventilation.

   Rochester, Minn.

   The purpose of this study is to evaluate whether or not the diaphragm and abdominal muscle thickness determine the duration of mechanical ventilation in adult critically ill patients.

3. COVID-19 and Acute Renal Failure

   Jacksonville, Fla., Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The primary purpose of this study is to examine 1-year survival and rate of secondary infections in COVID-19 patients with and without acute kidney injury (AKI).

    

    

    

4. A Study to Identify Risk Factors for 30-Day Readmission

   Rochester, Minn.

   The primary purpose of this study is to collect data on patient-identified factors which contribute to readmissions to the Mayo Clinic Hospital Medicine Services within 30 days of discharge.

5. A Study to Evaluate Biomarkers of Fluoroquinolone-induced Mitochondrial Toxicity

   Rochester, Minn.

   The purposes of this study are to determine if patients treated with fluoroquinolone (FQ) antibiotics have depletion of mitochondrial DNA (mtDNA) in buccal swab samples, and whether the degree of depletion correlates with the likelihood of developing FQ-associated toxicity.

   2nd arm - An additional group of patients will be enrolled if they previously received FQ antibiotics. appear to be symptomatic and have a previously collected muscle or nerve biopsy for clinical purposes available for this research study. 

6. Biospecimens Resource for Glomerular and Tubulo-interstitial Diseases

   Rochester, Minn.

   This study is being done to create a "resource" of samples that can be used to improve our ability to diagnose and treat MN, IgAN, MPGN, FSGS/MCD, Lupus Nephritis, AAV, other glomerular tubulo-interstitial disease.

7. Hospital Diuretic Therapy and Associated Risk of Heart Failure in Treating Fluid Volume Overload

   Rochester, Minn.

   The objective of this proposal is to assess blood-plasma volume (TBV-PV) status quantitatively in patients with DHF admitted to hospital for volume management, and to determine how effective standard diuretic therapy is in achieving euvolemia and the impact of their quantitated volume status at the time of hospital discharge on heart failure related morality and re-hospitalizations. Thus, to determine if quantitative blood volume analysis could potentially serve as an effective tool to guide more effective in-hospital diuretic therapy to achieve better outcomes in patients hospitalized with clinically identified volume overload.

8. A Study of Human Stem Cells from First Teeth in Humans

   Rochester, Minn.

   The purpose of this study is to isolate and characterize human stem cells from exfoliated first teeth.

9. A Study of Bone Microstructure and Bone Strength Using High-Resolution CT Scanning in Adults with Repeat Fractures

   Rochester, Minn.

   The purpose of this study is to obtain more detailed information about bone structure in adults with repeat bone fractures.

    

10. A Multimodal Monitoring (MMM) Computer to Detect Physiologic Trends in Data in Neurointensive Care Unit Patients

    Rochester, Minn., Jacksonville, Fla.

    The purpose of this study is to identify important physiologic trends in bedside ICU data such as cerebral perfusion pressure (CPP), intracranial pressure (ICP) using a bedside “Multimodal monitoring” (MMM) computer which utilizes ICM+ Cambridge software.