Clinical trials Below are current clinical trials.26 studies in Otolaryngology (ENT)/Head and Neck Surgery (open studies only). Filter this list of studies by location, status and more. A Study to Examine Proteins from Chronic Otitis Media Fluid Samples in Patients undergoing Myringotomy and Possibly a Tube Insertion Procedure Scottsdale/Phoenix, Ariz., Rochester, Minn. During myringotomy and possibly a tube insertion procedure a small amount of fluid that is being removed from the middle ear (whether or not you participate in the study) will be examined for different proteins or it may be saved and used for future research studies. A Study to Evaluate Electrophysiological Measurements in Cochlear Implant Patients Rochester, Minn. The purpose of this study is to perform electrophysiological (inner ear) measurements to assess hearing function in cochlear implant patients. A Study to Develop a Vestibular and Balance Function Measure (VBFM) Tool Rochester, Minn. The purpose of this study is develop a tool called the Vestibular and Balance Function Measure (VBFM) to evaluate vertigo, dizziness, or balance problems that affect patients; ability to perform tasks and participate in activities. Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck Rochester, Minn. This randomized phase II/III trial studies how well radiation therapy works when given together with cisplatin compared to docetaxel or cetuximab and docetaxel after surgery in treating patients with stage III-IV squamous cell head and neck cancer. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or transmit tumor killing molecules to them. It is not yet known whether radiation therapy is more effective when given with cisplatin, docetaxel, or cetuximab and docetaxel. A Study to Evaluate Endoscopic Endonasal Skull Base Surgery and Pituitary Surgery Quality of Life Rochester, Minn. The objectives of this study are to: Measure the short and long-term overall and nasal-specific quality of life (QOL) impact of patients undergoing Endoscopic Endonasal Skull Base Surgery (EESBS) for pituitary and sellar lesions. Determine the relative difference in QOL impact of EESBS for patients undergoing surgery for functional and nonfunctional pituitary adenomas. Generate baseline data to development and validate a site-specific endoscopic-specific comprehensive QOL for EESBS. Particular tumors of interest include pituitary tumors, Rathke’s cleft cysts, craniopharyngiomas, clival chordomas and chondrosarcomas. Specific QOL aims focus on olfaction (sense of smell), gustation (sense of taste) and nasal function. A Study of Factors That Predispose, Promote, and Perpetuate Post-Traumatic Dizziness Rochester, Minn. The purpose of this study is to investigate whether recent, groundbreaking discoveries about key pathophysiologic processes that drive chronic dizziness in patients without traumatic brain injury (TBI9,10) are applicable to patients with post-mTBI vestibular disability. We expect the results of this project to have practical clinical and research applications, providing novel data for two future steps: Neurological Diseases Co-existing in Patients with Spasmotic Dsyphonia (SD) Jacksonville, Fla. The purpose of this study is to investigate if spasmotic dsyphonia (SD) patients have neurological diseases like dystonia, cervical dystonia, Parkinson’s disease more than normal population Cricopharyngeal Dysfunction and Esophageal Diverticulum Rochester, Minn., Jacksonville, Fla. Patients undergoing open transcervical or endoscopic approach in which a laser or stapler is used to divide the common wall between the diverticulum and esophagus, or who are not surgical candidates but agree to follow-up. Epidemiologic and Psychologic Factors for Spasmotic Dsyphonia (SD) Jacksonville, Fla. The purpose of this study is to investigate the epidemiologic and psychologic factors for spasmotic dsyphonia (SD). Hearing Genomics Rochester, Minn. Aims, purpose, or objectives: 1) Develop hypotheses related to how the human genome and genetic variants affect hearing loss in children and adults. 2) Understand phenotypes of hearing loss on a deeper level by combining and analyzing information from audiometric, genetic, and radiologic data. 3) Explore genetic variants with an unknown significance to develop an understanding of their potential significance and explore other genes may influence an individual's hearing ability. Pagination Clinical studies Go to page 11 Go to page 22 Go to page 33 NextNext Page Request an appointment Specialty groupsResearch July 09, 2024 Share on: FacebookTwitter Show references Otolaryngology (ENT)/Head and Neck SurgerySectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsDoctors by location and specialtySpecialty groupsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsDoctors by location and specialtySpecialty groupsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20424058 Medical Departments & Centers Otolaryngology (ENT)/Head and Neck Surgery