Otorhinolaryngology (ENT)/Head and Neck Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Assess the Role of Technology for the Detection of Hearing Loss

   Rochester, Minn.

   The purpose of this study is to evaluate available tablet-based technology that can be easily used to screen and monitor patients for the detection of hearing loss in a quiet, clinic setting.

2. A Study to Examine Proteins from Chronic Otitis Media Fluid Samples in Patients undergoing Myringotomy and Possibly a Tube Insertion Procedure

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   During myringotomy and possibly a tube insertion procedure a small amount of fluid that is being removed from the middle ear (whether or not you participate in the study) will be examined for different proteins or it may be saved and used for future research studies.

3. A Study to Determine the Feasibility of Doppler Ultrasound of Large Arterial Systems of the Brain as Vascular Involvement Markers in Presbyacusis and Presbyvestibulopathy

   Jacksonville, Fla.

   The purpose of this study is to benchmark the feasibility of carotid artery biomechanical analysis and vertebral-basilar Transcranial Doppler (TCD) as markers of vascular involvement in presbyacusis and presbyvestibulopathy.

4. A Study to Evaluate Electrophysiological Measurements in Cochlear Implant Patients

   Rochester, Minn.

   The purpose of this study is to perform electrophysiological (inner ear) measurements to assess hearing function in cochlear implant patients.

    

    

5. Otorhinolaryngology Normal, Tumor Tissue, Saliva, Stool, and Blood Bank

   Rochester, Minn.

   The purpose of this study is to obtain tissue, blood, saliva, and stool specimens and informed consent from ENT patients in order to build a freezer archive of samples to support ongoing and future developmental studies.

6. A Study Identifying Blood Serum Markers of the Immune System Affecting Different Features of Chronic Rhinosinusitis

   Rochester, Minn.

   The purpose of this study is to find out what immune system processes cause the chronic inflammation that happens with chronic rhinosinusitis (CRS) and if there are different immune system pathways involved among CRS patients.

7. Study of the Preceptis Medical Inc. Hummingbird™ Tympanostomy Tube System in the Otolaryngology Clinic

   Rochester, Minn.

   The objective of this study is to evaluate the safety and performance of the H-TTS for the placement of ear tubes in patients undergoing tympanostomy tube placement in an otolaryngology clinic using local anesthetic.

8. A Study of Pain Control Following Sinus Surgery

   Rochester, Minn.

   The purpose of this study is to determine the degree to which pain following ESS can be adequately controlled by non-opioid medications. It will also determine whether post-ESS narcotic use can be avoided entirely, or at least significantly limited.  The results of this study will help to develop a standardized approach to pain management in the post-ESS setting and help to clarify the role of non-opioid pain medications. The ultimate goal would be to positively affect opioid prescribing patterns among surgeons who perform ESS in order to significantly reduce the quantity of opioids prescribed to patients while continuing to adequately manage patients' pain.

    

    

9. A Study of Genital Cytology and Pathology in Patients with Confirmed HPV Associated Oropharyngeal Carcinoma

   Rochester, Minn.

   The purpose of this study is to determine the incidence of concomitant HPV associated genital lesions in female patients with confirmed HPV associated oropharyngeal cancers, to determine the risk of requiring additional procedures or treatments secondary to these diagnoses, and to determine the HPV subtypes and other risk factors associated with genital dysplasia among those with documented HPV status.

10. Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) Versus Intensity-Modulated Photon Therapy (IMRT) for the Treatment of Oropharyngeal Cancer of the Head and Neck

    Scottsdale/Phoenix, Ariz., Rochester, Minn.

    The overall goal of this trial is to identify a less toxic approach to the delivery of conformal radiation therapy for patients with cancers of the oropharynx.