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Jay W. Schneider, M.D., Ph.D.

  1. Cardiologist
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Departments

Location

  1. Jacksonville, Florida

Languages

English

Existing patients

Jay W. Schneider, M.D., Ph.D., Vice Chair, Cardiovascular Research — Mayo Clinic Florida

Dr. Schneider is a cardiologist at Mayo Clinic Florida who focuses on helping adults maintain heart health throughout life. As Vice Chair for Cardiovascular Research, he combines clinical care with innovative research to prevent heart failure and promote “cardiolongevity”—strategies that support healthy aging of the heart.

He earned his M.D. and Ph.D. at Yale University and completed internal medicine training at Brigham and Women's Hospital/Harvard Medical School. His clinical interests include prevention, heart failure management, and personalized approaches to cardiovascular wellness.

Dr. Schneider's research explores how heart muscle cells change with age and how these insights can lead to new therapies. Patients appreciate his clear communication, collaborative care, and focus on practical steps that fit individual goals.

  1. Atrial fibrillation
  2. Cardiac amyloidosis
  3. Cardiomyopathy
  4. Coronary artery disease
  5. Heart palpitations
  6. Heart valve disease
  7. High blood cholesterol
  8. High blood pressure
  9. Hyperlipidemia
  10. Hypertrophic cardiomyopathy
  11. POTS
  • Cardiac aging and cardiolongevity, applying aging‑science principles to help patients maintain heart function across the lifespan.
  • Age‑related heart failure prevention and management, guided by research on structural and molecular changes of the aging heart.
  • Diagnosis and management of cardiac amyloidosis, with ongoing involvement in Mayo Clinic's Amyloid Interest Group.
  • Special interest in cardiovascular biomineralization and coronary artery calcium, including emerging mechanisms linking mineralization pathways to cardiac aging.
  • Exploring cross‑disciplinary insights between marine bioscience and heart disease, including analogies between seashell biosynthesis and pathological cardiovascular mineralization.
  • Personalized cardiovascular wellness strategies for older adults using precision diagnostics and tailored prevention plans.
  • Patient‑centered care, emphasizing clear communication, shared decision‑making, and practical guidance.
  1. 1997
    Clinical Fellowship - Cardiovascular DiseasesBrigham and Women's Hospital, Harvard Medical School
  2. 1997
    Postdoctoral Research Fellowship - Cardiovascular Medicine - Bernardo Nadal-Ginard, MD, PhD; Thomas W. Smith, MD; James A. DeCaprio, MDHarvard Medical School
  3. 1994
    Resident - Internal MedicineBrigham and Women's Hospital, Harvard Medical School
  4. 1991
    Internship - Internal Medicine; Eugene Braunwald Research/Residency "Hemi-doc" Program Brigham and Women's Hospital, Harvard Medical School
  5. 1990
    MD / PhD - NIH-Medical Scientist Training Program - Humans Genetics (Thesis Advisor: Edward J. Benz, Jr., MD) Yale University Graduate School
  6. 1982
    BA - Biochemistry and Cell Biology with HonorsUniversity of California San Diego

Certifications

  1. 2001
    Cardiovascular DiseasesAmerican Board of Internal Medicine

Awards and honors

  1. 2024
    Mayo Clinic Florida 2023 Top Performer Award, 99% Top Box Care Provider Award, Likelihood to RecommendPatient Experience Provider Recognition Award
  2. 2024
    Mayo Clinic Amyloid Interest Group TEAMS Recognition AwardMayo Clinic in Florida
  3. 2023
    FIVE Year Anniversary with Mayo Clinic Service Award Mayo Clinic Service Excellence
  4. 2013
    Endowed Chair for Cardiac ResearchThe Dallas Heart Ball, President's Office
  5. 2012
    Selected participant, LEAD (Leadership Emerging in Academic Departments) ProgramUniversity of Texas Southwestern Medical Center
  6. 2010
    Top downloaded online first article- "A dynamic notch injury response activates epicardium and contributes to fibrosis repair"Circulation Research
  7. 2010
    Thank you letters from President Daniel Podolsky, MD and Mary Ellen Weber, PhD, VP, Government Affairs and Policy for giving talks and tours to official legislative guestsUniversity of Texas Southwestern Medical Center
  8. 2009
    Letter of congratulations from UT Chancellor for U01 Award by Dr. Francisco G. Cigarroa, MDThe University of Texas at Dallas
  9. 1996
    Cardiovascular Young Investigator AwardAstraZeneca
  10. 1992
    Henry Christian Memorial Award for Excellence in Cardiovascular Research American Federation of Clinical Research
  11. 1992
    Finalist, Louis N. Katz Prize for Young InvestigatorsAmerican Heart Association
  12. 1992
    AFCR Trainee Investigator AwardAmerican Federation of Clinical Research
  13. 1991
    MD/PhD Postdoctoral Fellowship AwardMerck-American Federation of Clinical Research
  14. 1991
    AFCR Trainee Investigator AwardAmerican Federation of Clinical Research
  15. 1989
    Peter F. Curran Prize for Outstanding Medical School ThesisYale University School of Medicine

Professional memberships

  1. 2020 - 2021
    Co-DirectorTodd and Karen Wanek Program for Hypoplastic Left Heart Syndrome, Mayo Clinic
  2. 2017 - present
    MemberCardio Advisory Panel, Recombinetics, Inc
  3. 2015 - 2019
    Administrative Associate DirectorMyoediting Core, NIH-Wellstone Muscular Dystrophy Research Network Center for Excellence, University of Texas Southwestern Medical Center
  4. 2012
    Organizer2012 NIH/NHLBI Progenitor Cell Biology Consortium 4th Annual Meeting, University of Texas Southwestern Medical Center
  5. 2011 - 2019
    MemberStem Cell Stakeholder's Committee, Texas Medical Association
  6. 2010 - 2019
    Medical Advisory CounselTexans for Stem Cell Research
  7. 2010 - 2019
    President-Appointed ChairSan Yatsen University/UT Southwestern Postdoctoral Research Exchange Program, University of Texas Southwestern Medical Center
  8. 2010
    OrganizerJon Holden DeHaan Cardiac Myogenesis Research Centers 1st Annual Scientific Retreat, University of Texas Southwestern Medical Center
  9. 2010 - present
    MemberNIH/NHLB1 Progenitor Cell Biology Consortium Steering Committee, National Institutes of Health
  10. 2009 - 2019
    LeaderPresidential Dignitary Committee, University of Texas Southwestern Medical Center
  11. 2009 - 2016
    Administrative DirectorNIH/NHLBI-U01 Progenitor Cell Biology Consortium Group, University of Texas Southwestern Medical Center
  12. 2009 - 2013
    Administrative DirectorAmerican Heart Association-Jon Holden-DeHaan Cardiac Myogenesis Research Center, University of Texas Southwestern Medical Center
  13. 2004 - 2014
    DirectorCardiovascular Symposium: Chemical Genetics and Cardiovascular Drug Discovery, University of Texas Southwestern Medical Center
  14. 1997 - 2003
    DirectorCardiology Moonlighting Program, Brigham and Women's Hospital

Publications